Perfluorochemicals (PFCs) are highly fluorinated, inert organic compounds that can dissolve
large volumes of O2 and other respiratory gases. PFCs are unreactive in the body and …

Blood transfusion is a remarkably safe, routine clinical procedure. However, the need for
sophisticated blood processing, storage and cross-matching, coupled with increasing …

Concerns about blood safety and the logistical problems associated with conventional
transfusion have fuelled the search for effective alternatives (so-called blood substitutes) …

Oxygent™ is a stable concentrated perfluorochemical (PFC) emulsion being developed for
use as a temporary oxygen carrier. In this application, PFC emulsions can be used to …

A viable blood substitute is still of great necessity throughout the world. Perfluorocarbon‐
based oxygen carriers (PFCOCs) are emulsions that take advantage of the high solubility of …

Recent advances in the development and assessment of synthetic oxygen transport fluids
based on perfluorochemicals (PFCs) are reviewed. The basic properties of PFCs are …

Review: Biomedical applications of perfluorinated compounds, which are either dense white
powders or colorless, odorless liquids, are based on their gas transport capabilities and …

The basic properties of perfluorocarbons (PFCs) and PFC emulsions relevant to their use as
oxygen delivery systems are briefly reviewed. The key issues related to the selection of an …

There has been rapid progress in research on artificial oxygen-carrying red blood cell
substitutes composed of perfluorochemical emulsions (PFE). PFE are capable of delivering …

The risks of allogeneic transfusion are well known to physicians and have prompted a
search for alternatives. Perfluorocarbons were introduced into clinical trials in the early …