Objectives. To describe the extent of pain relief two weeks after an epidural steroid injection
in patients with herniated disks and lumbar spinal stenosis, and to identify predictors of …

Background Current evidence suggests that spinal manipulative therapy (SMT) is effective in
the treatment of people with low back pain (LBP); however, the corresponding mechanisms …

This study examined factors that help to identify low back pain patients who do not benefit
from a lumbar epidural steroid injection (LESI). Two-hundred and forty-nine chronic low back …

Low back pain is associated with plasticity changes and central hypersensitivity in a subset
of patients. We performed a case-control study to explore the discriminative ability of …

Sensitization to continued nociceptive stimulation is supposed to be involved in the
development of chronic pain at several levels of the CNS, but experimental studies …

Methods In this randomized, placebo-controlled and double-blinded cross-over study, 50
patients with chronic low-back pain received a single oral dose of oxycodone 15 mg or …

The most frequent clinical presentation of sciatica suggests injury of sensor root fibers alone.
To evaluate whether thermal quantitative sensory testing (QST) is applicable in the study of …

Objective The purpose of this observational study was to examine the association of protein
and genetic biomarkers with pain and pain-related disability in individuals with axial low …

Sex differences in clinical and experimental pain responses have been widely reported;
however, few studies have examined sex differences in outcomes from interventional pain …

Lumbar sympathetic block (LSB) is used in the management of sympathetically maintained
pain states. We characterized cutaneous temperature changes over the lower extremities …