Antimicrobial peptides: therapeutic potentials

SJ Kang, SJ Park, T Mishig-Ochir… - Expert review of anti …, 2014 - Taylor & Francis
The increasing appearance of multidrug-resistant pathogens has created an urgent need for
suitable alternatives to current antibiotics. Antimicrobial peptides (AMPs), which act as …

Antimicrobial peptides—Mechanisms of action, antimicrobial effects and clinical applications

J Talapko, T Meštrović, M Juzbašić, M Tomas, S Erić… - Antibiotics, 2022 - mdpi.com
The growing emergence of antimicrobial resistance represents a global problem that not
only influences healthcare systems but also has grave implications for political and …

Antimicrobial peptides: new drugs for bad bugs?

JD Steckbeck, B Deslouches… - Expert opinion on …, 2014 - Taylor & Francis
Antibiotics have been among the most successful classes of therapeutics and have enabled
many of modern medicine's greatest advances. However, antibiotic-resistant bacteria are …

Will new generations of modified antimicrobial peptides improve their potential as pharmaceuticals?

NK Brogden, KA Brogden - International journal of antimicrobial agents, 2011 - Elsevier
The concept of antimicrobial peptides (AMPs) as potent pharmaceuticals is firmly
established in the literature, and most research articles on this topic conclude by stating that …

Antimicrobial peptides under clinical investigation

HB Koo, J Seo - Peptide Science, 2019 - Wiley Online Library
Overuse of conventional antibiotics as well as the slow pace of new antibiotic drug
development leads to antimicrobial resistance (AMR). Because infections with multi‐drug …

Antimicrobial peptides: diversity, mechanism of action and strategies to improve the activity and biocompatibility in vivo

P Kumar, JN Kizhakkedathu, SK Straus - Biomolecules, 2018 - mdpi.com
Antibiotic resistance is projected as one of the greatest threats to human health in the future
and hence alternatives are being explored to combat resistance. Antimicrobial peptides …

[图书][B] Antimicrobial peptides: basics for clinical application

K Matsuzaki - 2019 - Springer
Antimicrobial peptides (AMPs) discovered about 30 years ago are responsible for part of the
innate immunity of animals and plants, and almost 3000 peptides have been reported so far …

Antimicrobial peptides: from design to clinical application

C Zhang, M Yang - Antibiotics, 2022 - mdpi.com
Infection of multidrug-resistant (MDR) bacteria, such as methicillin-resistant Staphylococcus
aureus (MRSA), carbapenem-resistant Enterobacteriaceae (CRE), and extended-spectrum …

Rediscovery of antimicrobial peptides as therapeutic agents

M Ryu, J Park, JH Yeom, M Joo, K Lee - Journal of Microbiology, 2021 - Springer
In recent years, the occurrence of antibiotic-resistant pathogens is increasing rapidly. There
is growing concern as the development of antibiotics is slower than the increase in the …

The therapeutic applications of antimicrobial peptides (AMPs): a patent review

HK Kang, C Kim, CH Seo, Y Park - Journal of microbiology, 2017 - Springer
Antimicrobial peptides (AMPs) are small molecules with a broad spectrum of antibiotic
activities against bacteria, yeasts, fungi, and viruses and cytotoxic activity on cancer cells, in …