Hsian-tsao (Mesona procumbens Heml.) prevents against rat liver fibrosis induced by CCl4 via inhibition of hepatic stellate cells activation

MH Shyu, TC Kao, GC Yen - Food and chemical toxicology, 2008 - Elsevier
In this study, the protective effect of extract of Hsian-tsao (Mesona procumbens)(EHT)
against liver fibrogenesis in carbon tetrachloride (CCl4)-injured rats was evaluated. The …

Anti-fibrotic effect of thymoquinone on hepatic stellate cells

M Ghazwani, Y Zhang, X Gao, J Fan, J Li, S Li - Phytomedicine, 2014 - Elsevier
Hepatic stellate cells (HSCs) are the major cell type involved in the production of
extracellular matrix in liver. After liver injury, HSCs undergo transdifferentiation process from …

Effect and mechanism of methyl helicterate isolated from Helicteres angustifolia (Sterculiaceae) on hepatic fibrosis induced by carbon tetrachloride in rats

Q Huang, Y Li, S Zhang, R Huang, L Zheng… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Methyl helicterate is a triterpenoid isolated
from Helicteres angustifolia (Sterculiaceae), one of the valuable traditional Chinese herbs …

Protective effects of seed melon extract on CCl4-induced hepatic fibrosis in mice

YY Zhan, JH Wang, X Tian, SX Feng, L Xue… - Journal of …, 2016 - Elsevier
Ethnopharmacological relevance Citrullus lanatus ssp. vulgaris var. megalaspermus Lin et
Chao, was also known as watermelon belongs to family Cucurbitaceae, variously used as …

Anti-fibrotic effects of Cuscuta chinensis with in vitro hepatic stellate cells and a thioacetamide-induced experimental rat model

JS Kim, S Koppula, MJ Yum, GM Shin… - Pharmaceutical …, 2017 - Taylor & Francis
Abstract Context: Cuscuta chinensis Lam.(Convolvulaceae) has been used as a traditional
herbal remedy for treating liver and kidney disorders. Objective: Anti-fibrotic effects of C …

Camellia oil (Camellia oleifera Abel.) attenuates CCl 4-induced liver fibrosis via suppressing hepatocyte apoptosis in mice

X Lei, Q Liu, Z Cao, J Zhang, T Kuang, Y Fang, G Liu… - Food & function, 2020 - pubs.rsc.org
Liver fibrosis is a common part of the pathological development of many chronic liver
diseases. As liver fibrosis progresses, it may lead to cirrhosis, portal hypertension, liver …

Methyl helicterate protects against CCl4-induced liver injury in rats by inhibiting oxidative stress, NF-κB activation, Fas/FasL pathway and cytochrome P4502E1 level

X Lin, R Huang, S Zhang, L Zheng, L Wei, M He… - Food and Chemical …, 2012 - Elsevier
This study was designed to investigate the protective effects of the methyl helicterate (MH)
isolated from Helicteres angustifolia L. against CCl4-induced hepatotoxicities in rats. Liver …

[HTML][HTML] Emodin protects rat liver from CCl4-induced fibrogenesis via inhibition of hepatic stellate cells activation

MX Dong, Y Jia, YB Zhang, CC Li… - World journal of …, 2009 - ncbi.nlm.nih.gov
AIM: To investigate the role of emodin in protecting the liver against fibrogenesis caused by
carbon tetrachloride (CCl 4) in rats and to further explore the underlying mechanisms …

Danggui Shaoyao San: Chemical characterization and inhibition of oxidative stress and inflammation to treat CCl4-induced hepatic fibrosis

Y Zhao, M Zhao, Z Wang, C Zhao, Y Zhang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Danggui Shaoyao San (DSS) has effective in
treating hepatic ascites and liver disease. Aim of the study To explore the chemical …

Hemistepsin A alleviates liver fibrosis by inducing apoptosis of activated hepatic stellate cells via inhibition of nuclear factor-κB and Akt

JK Kim, NR Han, SM Park, KH Jegal, JY Jung… - Food and Chemical …, 2020 - Elsevier
Hemistepsin A (HsA), isolated from Hemistepta lyrata (Bunge) Bunge, has the ability to
ameliorate hepatitis in mice. However, the effects of H. lyrata and HsA on other types of liver …