The fabrication of aptamers on DNA nanostructures through the DNA origami method has
shown great potential for in vitro and in vivo tumor targeting delivery. Herein, tetrahedral …

In spite of great development in nanoparticle-based drug delivery systems (DDSs) for
improved therapeutic efficacy, it remains challenging for effective delivery of …

Drug resistance is a major obstacle to the efficient therapy of drug-resistant cancer. To
overcome this problem, we constructed a multifunctional DNA origami-based nanocarrier for …

Tetrahedral DNA nanostructures (TDNs) are considered promising drug delivery carriers
because they are able to permeate cellular membrane and are biocompatible and …

Due to the limitations of conventional cancer treatment methods, nanomedicine has
appeared as a promising alternative, allowing improved drug targeting and decreased drug …

We herein demonstrate that DNA origami can work as a multifunctional platform integrating
a chemotherapeutic drug (doxorubicin), gold nanorods and a tumour-specific aptamer MUC …

DNA origami technology, a unique type of DNA nanotechnology, has attracted much
attention from researchers and is applied in various fields. Through exquisite design and …

Active targeting of nanostructures containing chemotherapeutic agents can improve cancer
treatment. Here, a three-way junction pocket DNA nanostructure was developed for efficient …

By its unique advantages over traditional medicine, nanomedicine has offered new
strategies for cancer treatment. In particular, the development of drug delivery strategies has …

DNA can be used to nanofabricate three-dimensional (3D) polyhedra. A variety of
applications of 3D DNA assemblies have been proposed. Drug encasulation and …