The new kids on the block: RNA‐binding proteins regulate autophagy in disease
S Dushnitzky, H Ishtayeh, A Ashkenazi - The FEBS Journal, 2024 - Wiley Online Library
Mammalian autophagy is a highly regulated and conserved cellular homeostatic process. Its
existence allows the degradation of self‐components to mediate cell survival in different …
existence allows the degradation of self‐components to mediate cell survival in different …
Towards understanding mRNA-binding protein specificity: lessons from post-transcriptional regulation of ATG mRNA during nitrogen starvation-induced autophagy
D Gatica, DJ Klionsky - Current genetics, 2019 - Springer
In this report, we discuss recent discoveries concerning the effects and specificity of different
RNA-binding proteins (RBPs) as they pertain to macroautophagy/autophagy. Autophagy is a …
RNA-binding proteins (RBPs) as they pertain to macroautophagy/autophagy. Autophagy is a …
Post-transcriptional dynamics and RNA homeostasis in autophagy and cancer
SP Kolapalli, TM Nielsen, LB Frankel - Cell Death & Differentiation, 2023 - nature.com
Autophagy is an essential recycling and quality control pathway which preserves cellular
and organismal homeostasis. As a catabolic process, autophagy degrades damaged and …
and organismal homeostasis. As a catabolic process, autophagy degrades damaged and …
The autophagy–RNA interplay: degradation and beyond
MH Abildgaard, SH Brynjólfsdóttir, LB Frankel - Trends in Biochemical …, 2020 - cell.com
Autophagy is a highly conserved degradation pathway that ensures nutrient recycling and
removal of unwanted substrates. This process has a fundamental role in stress adaptation …
removal of unwanted substrates. This process has a fundamental role in stress adaptation …
Translational repression stabilizes messenger RNA of autophagy‐related genes
In response to amino acid starvation, autophagy mediates the lysosome‐dependent
turnover of cytosolic components via autophagosome formation. Despite advances in …
turnover of cytosolic components via autophagosome formation. Despite advances in …
The Pat1-Lsm complex prevents 3′ to 5′ degradation of a specific subset of ATG mRNAs during nitrogen starvation-induced autophagy
Deregulation of macroautophagy/autophagy, a conserved catabolic recycling pathway, has
been implicated in the onset and development of several diseases. While post-translational …
been implicated in the onset and development of several diseases. While post-translational …
Emerging connections between RNA and autophagy
LB Frankel, M Lubas, AH Lund - Autophagy, 2017 - Taylor & Francis
Macroautophagy/autophagy is a key catabolic process, essential for maintaining cellular
homeostasis and survival through the removal and recycling of unwanted cellular material …
homeostasis and survival through the removal and recycling of unwanted cellular material …
The role of epigenetics and non-coding RNAs in autophagy: A new perspective for thorough understanding
Autophagy is a major self-degradative intracellular process required for the maintenance of
homeostasis and promotion of survival in response to starvation. It plays critical roles in a …
homeostasis and promotion of survival in response to starvation. It plays critical roles in a …
Regulated degradation: controlling the stability of autophagy gene transcripts
H Nakatogawa - Developmental Cell, 2015 - cell.com
Autophagy is involved in diverse cellular functions through degradation of various
intracellular constituents, and hence must be tightly controlled. A recent study by Hu et …
intracellular constituents, and hence must be tightly controlled. A recent study by Hu et …
Long non-coding RNAs involved in autophagy regulation
Autophagy degrades non-functioning or damaged proteins and organelles to maintain
cellular homeostasis in a physiological or pathological context. Autophagy can be protective …
cellular homeostasis in a physiological or pathological context. Autophagy can be protective …