Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system. The
disease manifestation is associated with the proliferation and activation of lymphocytes and …

Inflammatory mediators play a crucial role in the pathophysiology of several
neurodegenerative diseases including acquired immune deficiency syndrome dementia …

A broad spectrum of diseases is characterized by myelin abnormalities and/or
oligodendrocyte pathology. In most, if not all, of these diseases, early activation of microglia …

Background CXCR7 and CXCR4 are receptors for the chemokine CXCL12, which is
involved in essential functions of the immune and nervous systems. Although CXCR7 …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system (CNS). It affects more than two million people worldwide, mainly young …

Chemokines direct cellular infiltration to tissues, and their receptors and signaling pathways
represent targets for therapy in diseases such as multiple sclerosis (MS). The chemokine …

Objective: Differentiation of oligodendroglial precursor cells is crucial for central nervous
system (re) myelination and is influenced by multiple extrinsic and intrinsic factors …

Background Multiple sclerosis (MS) is a chronic debilitating immune-mediated disease of
the central nervous system (CNS) driven by demyelination and gray matter …

The etiology of several autoimmune diseases, including multiple sclerosis (MS) is still not
clarified. MS is defined as an autoimmune disease with clinical features of a chronic …

Lymphoid chemokines are crucial for the development and maintenance of lymphoid
organs, but their ectopic expression in non‐lymphoid tissues is implicated in both local …