The response characteristics of lamina I neurones recorded extracellularly in the
lumbosacral enlargement of chloralose‐anaesthetized cats were examined with peripheral …

Somatosensory pathways are subject to descending modulation from the brain (10, 26, 42,
57). The spinothalamic tract is believed to be the main somatosensory pathway in primates …

The organization in the brainstem of descending pathways of spinal inhibition was
examined in the lightly pentobarbital-anesthetized rat. Thresholds for focal electrical …

Norepinephrine and serotonin microinjections (10 μg) into the dorsal spinal gray matter
depressed C-fiber reflexes induced by electrical stimulation of the superficial peroneal nerve …

The majority of neurons at the origin of the spinocervical tract are driven by noxious
stimulation of their receptive fields. Surprisingly, previous studies have encountered only a …

It has been previously established that a bulbar relay plays an important role in descending
inhibition of spinal dorsal horn nociceptive neurons and nociceptive reflexes produced by …

Stimulation in the nucleus raphe magnus (NRM) of the medulla produces an analgesic state
in cats (35, 36) and rats (34, 39). It is likely that this is due at least in part to an action in the …

Recordings were made from neurons in subnucleus reticularis dorsalis of the rat. Two
populations of neurons could be distinguished: those with total nociceptive convergence …

Urban, MO and GF Gebhart. Characterization of biphasic modulation of spinal nociceptive
transmission by neurotensin in the rat rostral ventromedial medulla. J. Neurophysiol. 78 …

Neurons of the rostral ventromedial medulla (RVM) have been implicated in the modulation
of nociceptive transmission. In order to further analyze their role in pain behavior, we studied …