MAP kinases have been established to be key regulators of cellular signal transduction
systems and are conserved from baker's yeast to human beings. Until now, three major …

Mitogen-activated protein (MAP) kinases are a family of serine/threonine kinases that play a
central role in transducing extracellular cues into a variety of intracellular responses ranging …

Background Members of the MAP kinase superfamily play important roles in a wide variety
of signal transduction pathways, and several members have been identified. However, the …

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MAP kinases help to mediate diverse processes ranging from transcription of
protooncogenes to programmed cell death. More than a dozen mammalian MAP kinase …

Mitogen-activated protein kinases (MAPKs) are specifically phosphorylated and activated by
the MAPK kinases, phosphorylate various targets such as MAPK-activated protein kinases …

Mitogen‐activated protein (MAP) kinases are typical examples of protein kinases whose
enzymatic activity is mainly controlled by activation loop phosphorylation. The classical MAP …

In order to adapt to their environment, cells integrate extracellular signals through activation
of numerous signal transduction pathways that regulate their morphology, proliferation …

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Mitogen-activated protein (MAP) kinases require dual phosphorylation on threonine and
tyrosine residues in order to gain enzymatic activity. This activation is carried out by a family …