Current state of hypothermic machine perfusion preservation of organs: The clinical perspective

MJ Taylor, SC Baicu - Cryobiology, 2010 - Elsevier
This review focuses on the application of hypothermic perfusion technology as a topic of
current interest with the potential to have a salutary impact on the mounting clinical …

Machine perfusion of donor organs for transplantation

R Tatum, TJ O'Malley, AS Bodzin… - Artificial …, 2021 - Wiley Online Library
The ever‐widening gap between organ supply and demand has resulted in an organ
shortage crisis that affects patients all over the world. For decades, static cold storage (SCS) …

Novel Organ Perfusion and Preservation Strategies in Transplantation–Where Are We Going in the United Kingdom?

S O'Neill, S Srinivasa, CJ Callaghan, CJE Watson… - …, 2020 - journals.lww.com
This review article focuses on current clinical outcomes with novel perfusion strategies in
organ transplantation. Broadly, these approaches can be divided into in situ regional …

Machine perfusion or cold storage in organ transplantation: indication, mechanisms, and future perspectives

X Yuan, AJ Theruvath, X Ge… - Transplant …, 2010 - Wiley Online Library
Most organs are currently preserved by cold storage (CS) prior to transplantation. However,
as more so called marginal donor organs are utilized, machine perfusion has regained …

Perspectives in organ preservation

MHJ Maathuis, HGD Leuvenink, RJ Ploeg - Transplantation, 2007 - journals.lww.com
Maintaining organ viability after donation until transplantation is critically important for
optimal graft function and survival. To date, static cold storage is the most widely used form …

Hypothermic perfusion preservation: the future of organ preservation revisited?

BJ Fuller, CY Lee - Cryobiology, 2007 - Elsevier
Hypothermic perfusion preservation (HPP) was an integral step in the development of early
clinical transplantation programmes, and considerable progress was made in understanding …

Ex-vivo machine perfusion for kidney preservation

M Hamar, M Selzner - Current opinion in organ transplantation, 2018 - journals.lww.com
Ex-vivo machine perfusion represents a superior organ preservation method over static cold
storage. There is still an urgent need for the optimization of the perfusion fluid and machine …

The future of organ perfusion and re‐conditioning

A Weissenbacher, G Vrakas, D Nasralla… - Transplant …, 2019 - Wiley Online Library
Organ preservation and re‐conditioning using machine perfusion technologies continue to
generate promising results in terms of viability assessment, organ utilization and improved …

[HTML][HTML] Machine perfusion in abdominal organ transplantation: Current use in the Netherlands

E Rijkse, JNM IJzermans… - World journal of …, 2020 - ncbi.nlm.nih.gov
Scarcity of donor organs and the increment in patients awaiting a transplant increased the
use of organs from expanded criteria donors or donation after circulatory death. Due to the …

Bioengineering approaches to organ preservation ex vivo

M Pinezich… - Experimental Biology and …, 2019 - journals.sagepub.com
The advent of successful solid organ transplantation is undoubtedly among the most
significant medical achievements of the 20th century. Despite advances in the field of …