Depot testosterone with etonogestrel implants result in induction of azoospermia in all men for long-term contraception

BM Brady, M Walton, N Hollow, AT Kicman… - Human …, 2004 - academic.oup.com
BACKGROUND: Combined testosterone and progestogen preparations are a promising
approach to male hormonal contraception. We investigated the effect of sc etonogestrel with …

Levonorgestrel implants enhanced the suppression of spermatogenesis by testosterone implants: comparison between Chinese and non-Chinese men

C Wang, XH Wang, AL Nelson, KK Lee… - The Journal of …, 2006 - academic.oup.com
Context: Previous male contraceptive studies showed that progestins enhance
spermatogenesis suppression by androgens in men. Objective: We compared the efficacy of …

Metabolic and behavioral effects of high-dose, exogenous testosterone in healthy men

CJ Bagatell, JR Heiman, AM Matsumoto… - The Journal of …, 1994 - academic.oup.com
In addition to their use as replacement therapy for hypogonadal males, androgens,
particularly testosterone (T), are being explored as potential hormonal male contraceptive …

Drug insight: recent advances in male hormonal contraception

JK Amory, ST Page, WJ Bremner - Nature Clinical Practice …, 2006 - nature.com
As there are limitations to current methods of male contraception, research has been
undertaken to develop hormonal contraceptives for men, analogous to the methods for …

[HTML][HTML] Testosterone use in the male infertility population: prescribing patterns and effects on semen and hormonal parameters

MK Samplaski, Y Loai, K Wong, KC Lo, ED Grober… - Fertility and sterility, 2014 - Elsevier
Objective To analyze how frequently and why men presenting with infertility take
testosterone (T) and if negative effects of T on semen parameters are reversed following …

Suppression of spermatogenesis by etonogestrel implants with depot testosterone: potential for long-acting male contraception

RA Anderson, D Kinniburgh… - The Journal of Clinical …, 2002 - academic.oup.com
The coadministration of a progestogen with testosterone increases the degree of
suppression of spermatogenesis and is one approach to the development of hormonal male …

A multicentre study investigating subcutaneous etonogestrel implants with injectable testosterone decanoate as a potential long-acting male contraceptive

BM Brady, JK Amory, A Perheentupa… - Human …, 2006 - academic.oup.com
BACKGROUND: The combination of etonogestrel implants with injectable testosterone
decanoate was investigated as a potential male contraceptive. METHODS: One hundred …

[HTML][HTML] Comparison of two androgens plus depot-medroxyprogesterone acetate for suppression to azoospermia in Indonesian men

World Health Organization - Fertility and Sterility, 1993 - Elsevier
Objective To compare the sperm suppression in Indonesian men achieved by combination
treatment with either T enanthate or 19-nortestosterone-hexyloxy-phenyl-propionate (19 …

Levonorgestrel implants (Norplant II) for male contraception clinical trials: combination with transdermal and injectable testosterone

ITG Gonzalo, RS Swerdloff, AL Nelson… - The Journal of …, 2002 - academic.oup.com
Recent studies demonstrate that combinations of androgens and progestagens are highly
effective in the suppression of spermatogenesis in normal volunteers. To test whether …

Intramuscular testosterone undecanoate with or without oral levonorgestrel: a randomized placebo‐controlled feasability study for male contraception

A Kamischke, D PloÈger, S Venherm… - Clinical …, 2000 - Wiley Online Library
OBJECTIVE Approaches to hormonal male contraception are based on injectable
testosterone esters alone or in combination with gestagens or GnRH analogs but the short …