Treatment of multiple sclerosis—success from bench to bedside

M Tintore, A Vidal-Jordana… - Nature Reviews …, 2019 - nature.com
The modern era of multiple sclerosis (MS) treatment began 25 years ago, with the approval
of IFNβ and glatiramer acetate for the treatment of relapsing–remitting MS. Ten years later …

Update on disease-modifying therapies for multiple sclerosis

DL Vargas, WR Tyor - Journal of Investigative Medicine, 2017 - journals.sagepub.com
Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous
system (CNS). It predominantly affects young women and is one of the most common causes …

Multiple sclerosis: current knowledge and future outlook

CP Kamm, BM Uitdehaag, CH Polman - European neurology, 2014 - karger.com
Background: Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous
system characterized by demyelination and axonal loss. The etiology of MS is unknown; …

[HTML][HTML] Early aggressive treatment approaches for multiple sclerosis

A Simpson, EM Mowry, SD Newsome - Current treatment options in …, 2021 - Springer
Purpose of review This review presents a comprehensive analysis of the current high-
efficacy disease-modifying therapies (DMTs) available for treatment of multiple sclerosis …

Multiple sclerosis: pathogenesis and treatment

I Loma, R Heyman - Current neuropharmacology, 2011 - ingentaconnect.com
Multiple sclerosis (MS) is a chronic inflammatory autoimmune demyelinating disease of the
central nervous system. It affects approximately 400,000 people in the United States and …

Current disease‐modifying treatment of multiple sclerosis

J Derwenskus - Mount Sinai Journal of Medicine: A Journal of …, 2011 - Wiley Online Library
The treatment era for multiple sclerosis began in 1993 with the approval of the first disease‐
modifying therapy. This changed the management of multiple sclerosis from treating acute …

Comprehensive systematic review summary: Disease-modifying therapies for adults with multiple sclerosis: Report of the Guideline Development, Dissemination, and …

A Rae-Grant, GS Day, RA Marrie, A Rabinstein… - Neurology, 2018 - AAN Enterprises
Objective To review evidence on starting, switching, and stopping disease-modifying
therapies (DMTs) for multiple sclerosis (MS) in clinically isolated syndrome (CIS), relapsing …

Diagnosis and treatment of multiple sclerosis: a review

MP McGinley, CH Goldschmidt, AD Rae-Grant - Jama, 2021 - jamanetwork.com
Importance Multiple sclerosis (MS) is an autoimmune-mediated neurodegenerative disease
of the central nervous system characterized by inflammatory demyelination with axonal …

New approaches in the management of multiple sclerosis

LJ Barten, DR Allington, KA Procacci… - Drug design …, 2010 - Taylor & Francis
Multiple sclerosis (MS) is a central nervous system chronic inflammatory disease that is
characterized by an extensive and complex immune response. Scientific advances have …

Current and future therapies for multiple sclerosis

A Minagar - Scientifica, 2013 - Wiley Online Library
With the introduction of interferon‐β1b in 1993 as the first FDA‐approved treatment for
multiple sclerosis, the era of treatment of this incurable disease began, and its natural …