The activities in mouse retinae were evaluated after 6-hydroxydopamine injection. A
significant increase in labeled leucine uptake was evident in the photoreceptor layer. Latex …

Melanosoinal “tyrosinase”(L-dopa oxidase) was isolated from trypsin digests of B-16 mouse
melanoma melanosomes, using polyacrylamide gel disc electrophoresis. The enzyme was …

Dopachrome isomerase, which mediates the conversion of dopachrome to
dihydroxyindoles, is an enzyme affiliated with the melanogenic pathway found in most …

A melanin‐associated agent seems to play a role in regulating retinal development. When
absent, diverse deficits occur. There is evidence that this agent regulates patterns of mitosis …

The effect of prolonged exposure to light on the activity of dopaminergic neurons and
dopamine (DA) metabolism of chick retinae was investigated. α‐Fluoromethyldopa, a potent …

Oxidation of tyrosine in the presence of bovine lens proteins leads to the formation of brown
or black melanoproteins. Both tyrosinase and the oxidizing system of ferrous sulphate …

Histochemical studies have indicated that mammalian peroxidase can mediated the
conversion of tyrosine to melanin (in the presence of dopa co-factor) as well as the …

The hair follicles and the eyes of pallid mice (C57/6J-Pa/Pa) and those of black mice
(C57/6J−+/Pa) were examined ultrastructurally, histochemically, and biochemically to …

Melanogenesis has long been a subject of intense interest to the biochemist, the geneticist,
the embryologist, the pathologist, and the experimental physiologist because of its readily …