This open study of beta blockers in chronic simple glaucoma compared the efficacy of once
daily (od) oral nadolol therapy with twice daily (bd) topical timolol therapy. Sixty eight …

A preparation of timolol maleate for topical use was released in Britain in January 1979. By
December 1981, 50 000 patients with glaucoma were thought to be receiving treatment with …

AIM To determine the long term efficacy of monotherapy with topically applied β blocking
agents and to determine whether selective β blockers were able to preserve the visual field …

We studied the ocular hypotensive efficacy and safety of 0.5% levobunolol hydrochloride
and 0.5% timolol maleate administered topically once daily for 3 months in 91 patients (46 in …

We compared the effects of oral nadolol 20 mg once daily and topical timolol 0.25% twice
daily on the intraocular pressures of 22 glaucoma suspects, in a 12 week double-masked …

Many reported series of patients treated with topical Timolol for chronic open angle
glaucoma have been changed from other medication after a'wash-out'period. This four year …

• Regimens of once-a-day or twice-aday 0.25% timolol ophthalmic solution were compared
for efficacy and tolerability in a four-week study of 41 patients with chronic open-angle …

Although twice-daily instillation of topical beta-blockers is the standard regimen for treatment
of increased intraocular pressure, once-daily therapy might improve patient compliance and …

Topical β-blockers reduce the intraocular pressure (IOP) by blockade of sympathetic nerve
endings in the ciliary epithelium causing a fall in aqueous humour production. Two types of …

A group of 162 patients with chronic open-angle glaucoma or ocular hypertension were
treated twice daily for up to 15 months with one of the following topical ophthalmic solutions …