Sediment in urine may contain low-molecular-weight compounds that should be included in
the analysis. To date, no systematic investigation has addressed this issue. We investigated …

Developing a workflow for metabolite profiling from biological fluids using mass
spectrometry is imperative to extract accurate information. In this study, urine samples from …

Background Human urine gives evidence of the metabolism in the body and contains
different metabolites at various concentrations. A number of analytical techniques including …

Steps preceding introduction of the analytical sample into individual separation equipment
and/or mass-spectrometry (MS) detectors for targeted or untargeted metabolomics studies …

Urine metabolomics has recently emerged as a prominent field for the discovery of non‐
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …

Urine has long been a “favored” biofluid among metabolomics researchers. It is sterile, easy-
to-obtain in large volumes, largely free from interfering proteins or lipids and chemically …

This paper presents a simple and reliable gas chromatography/mass spectrometry (GC/MS)
method for the metabonomic analysis of human urine samples. The sample preparation …

There is a lack of comprehensive studies documenting the impact of sample collection
conditions on metabolic composition of human urine. To address this issue, two experiments …

Metabolomics represents an emerging issue that can aid in the diagnosis and/or prognosis
of different diseases. Metabolomic study of urine is particularly interesting as it can be on the …

A sensitive, accurate and precise method was developed for the quantification of a large
number of organic acids in human urine by GC-MS/MS. The analytes were selected based …