Dopamine D1 receptor gene expression decreases in the nucleus accumbens upon long-term exposure to palatable food and differs depending on diet-induced …

J Alsiö, PK Olszewski, AH Norbäck, ZEA Gunnarsson… - Neuroscience, 2010 - Elsevier
The nucleus accumbens (NAcc) mediates feeding reward; its activity reflects tastants'
hedonic value. NAcc dopamine guides immediate responses to reward, however, its …

Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats

PM Johnson, PJ Kenny - Nature neuroscience, 2010 - nature.com
We found that development of obesity was coupled with emergence of a progressively
worsening deficit in neural reward responses. Similar changes in reward homeostasis …

Repeated sucrose access influences dopamine D2 receptor density in the striatum

NT Bello, LR Lucas, A Hajnal - Neuroreport, 2002 - journals.lww.com
A decrease in D2 dopamine receptor subtype (D2R) binding in the striatum has been
reported in obese individuals and drug addicts. We examined D2R density in the striatum of …

Altered dopamine D2 receptor function and binding in obese OLETF rat

A Hajnal, WM Margas, M Covasa - Brain research bulletin, 2008 - Elsevier
A decrease in D2-like receptor (D2R) binding in the striatum has been reported in obese
individuals and drug addicts. Although natural and drug rewards share neural substrates, it …

Corrigendum: Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats.

PM Johnson, PJ Kenny - 2010 - psycnet.apa.org
Reports an error in" Dopamine D2 receptors in addiction-like reward dysfunction and
compulsive eating in obese rats" by Paul M. Johnson and Paul J. Kenny (Nature …

Low dopamine D2 receptor increases vulnerability to obesity via reduced physical activity, not increased appetitive motivation

JA Beeler, RP Faust, S Turkson, H Ye, X Zhuang - Biological psychiatry, 2016 - Elsevier
Background The dopamine D 2 receptor (D 2 R) has received much attention in obesity
studies. Data indicate that D 2 R is reduced in obesity and that the TaqA1 D 2 R variant may …

Reduced accumbens dopamine in Sprague–Dawley rats prone to overeating a fat-rich diet

P Rada, ME Bocarsly, JR Barson, BG Hoebel… - Physiology & …, 2010 - Elsevier
Obese humans and animals exhibit reduced functioning of the dopamine (DA) system in the
nucleus accumbens (NAc). The question addressed here is whether this change in NAc DA …

Deficits of mesolimbic dopamine neurotransmission in rat dietary obesity

BM Geiger, M Haburcak, NM Avena, MC Moyer… - Neuroscience, 2009 - Elsevier
Increased caloric intake in dietary obesity could be driven by central mechanisms that
regulate reward-seeking behavior. The mesolimbic dopamine system, and the nucleus …

Dopamine receptor subtype agonists and feeding behavior

P Terry, DB Gilbert, SJ Cooper - Obesity Research, 1995 - Wiley Online Library
Stimulation or blockade of various dopamine receptor subtypes is associated with reduced
feeding. For example, D2 receptor agonists suppress feeding in food‐deprived and free …

[HTML][HTML] Addiction-like reward dysfunction and compulsive eating in obese rats: Role for dopamine D2 receptors

PM Johnson, PJ Kenny - Nature neuroscience, 2010 - ncbi.nlm.nih.gov
We found that development of obesity was coupled with the emergence of a progressively
worsening brain reward deficit. Similar changes in reward homeostasis induced by cocaine …