[HTML][HTML] Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers
I Landa, T Ibrahimpasic, L Boucai… - The Journal of …, 2016 - Am Soc Clin Investig
BACKGROUND. Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer
(ATC) are rare and frequently lethal tumors that so far have not been subjected to …
(ATC) are rare and frequently lethal tumors that so far have not been subjected to …
[HTML][HTML] Clinical utility of TERT promoter mutations and ALK rearrangement in thyroid cancer patients with a high prevalence of the BRAF V600E mutation
Background Mutations in the TERT promoter, ALK rearrangement, and the BRAF V600E
mutation are associated with aggressive clinicopathologic features in thyroid cancers …
mutation are associated with aggressive clinicopathologic features in thyroid cancers …
Prognostic effects of TERT promoter mutations are enhanced by coexistence with BRAF or RAS mutations and strengthen the risk prediction by the ATA or TNM …
YS Song, JA Lim, H Choi, JK Won, JH Moon, SW Cho… - Cancer, 2016 - Wiley Online Library
BACKGROUND Recent reports suggest that mutations in the promoter of the gene encoding
telomerase reverse transcriptase (TERT) affect thyroid cancer outcomes. METHODS In all …
telomerase reverse transcriptase (TERT) affect thyroid cancer outcomes. METHODS In all …
TERT Promoter Mutations and Their Association with BRAF V600E Mutation and Aggressive Clinicopathological Characteristics of Thyroid Cancer
Context: Promoter mutations chr5: 1,295,228 C> T and chr5: 1,295,250 C> T (termed C228T
and C250T, respectively) in the gene for telomerase reverse transcriptase (TERT) have …
and C250T, respectively) in the gene for telomerase reverse transcriptase (TERT) have …
[HTML][HTML] In silico and in vitro analysis of rare germline allelic variants of RET oncogene associated with medullary thyroid cancer
B Cosci, A Vivaldi, C Romei… - Endocrine-Related …, 2011 - erc.bioscientifica.com
Mutations 1 295 228 C> T and 1 295 250 C> T (termed C228T and C250T respectively),
corresponding to− 124 C> T and− 146 C> T from the translation start site in the promoter of …
corresponding to− 124 C> T and− 146 C> T from the translation start site in the promoter of …
[HTML][HTML] TERT Promoter Mutations in Thyroid Cancer
Two mutations (C228T and C250T) in the promoter region of the telomerase reverse
transcriptase (TERT) have recently been described in different types of cancer including …
transcriptase (TERT) have recently been described in different types of cancer including …
TERT promoter mutations in thyroid cancer
M Matsuse, N Mitsutake - Endocrine journal, 2023 - jstage.jst.go.jp
TERT promoter mutations (TERT-p mutations) have been found in many types of cancer and
have emerged to play critical roles in tumor progression. The mutations upregulate TERT …
have emerged to play critical roles in tumor progression. The mutations upregulate TERT …
[HTML][HTML] Molecular features of aggressive thyroid cancer
G Elia, A Patrizio, F Ragusa, SR Paparo… - Frontiers in …, 2022 - frontiersin.org
Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC) have a
worse prognosis with respect to well differentiated TC, and the loss of the capability of up …
worse prognosis with respect to well differentiated TC, and the loss of the capability of up …
[HTML][HTML] TERT promoter mutations in thyroid cancer: a report from a Middle Eastern population
E Qasem, AK Murugan, H Al-Hindi… - Endocrine-related …, 2015 - erc.bioscientifica.com
Telomerase reverse transcriptase (TERT) promoter mutations C228T and C250T have
recently been described in follicular cell-derived thyroid cancer (TC) in patients from North …
recently been described in follicular cell-derived thyroid cancer (TC) in patients from North …
[HTML][HTML] The role of TERT promoter mutations in postoperative and preoperative diagnosis and prognosis in thyroid cancer
A Jin, J Xu, Y Wang - Medicine, 2018 - journals.lww.com
Background: Telomerase reverse transcriptase (TERT) promoter mutations have been
described in different pathological types of thyroid cancers (TC). After many types of …
described in different pathological types of thyroid cancers (TC). After many types of …