Investigating ROS sources in male infertility: a common end for numerous pathways

G Lavranos, M Balla, A Tzortzopoulou, V Syriou… - Reproductive …, 2012 - Elsevier
Reactive oxygen species (ROS) are active byproducts of aerobic metabolism. Although they
are constantly produced during normal cellular activities in the mitochondria, their action is …

Reactive oxygen species in male reproduction: A boon or a bane?

S Baskaran, R Finelli, A Agarwal, R Henkel - Andrologia, 2021 - Wiley Online Library
Reactive oxygen species (ROS) are free radicals derived from oxygen during normal cellular
metabolism. ROS play a crucial role in the physiological processes and signalling pathways …

From past to present: The link between reactive oxygen species in sperm and male infertility

AISB Villaverde, J Netherton, MA Baker - Antioxidants, 2019 - mdpi.com
Reactive oxygen species (ROS) can be generated in mammalian cells via both enzymatic
and non-enzymatic mechanisms. In sperm cells, while ROS may function as signalling …

Physiological role of ROS in sperm function

S Dutta, R Henkel, P Sengupta, A Agarwal - Male infertility: Contemporary …, 2020 - Springer
Oxygen, in its diatomic form, is essentially reduced to sustain cellular respiration and
survival. This reduction leads to generation of highly reactive oxygen metabolites or reactive …

Reactive oxygen species (ROS) and male fertility

S Tafuri, F Ciani, EL Iorio, L Esposito… - New discoveries in …, 2015 - books.google.com
Oxidative energy production is inevitably associated with the generation of reactive oxygen
species (ROS), excessive concentrations of which can lead to cellular pathology. A free …

Reactive oxygen species in the reproductive system: sources and physiological roles

A Das, S Roychoudhury - Oxidative Stress and Toxicity in Reproductive …, 2022 - Springer
Reactive oxygen species (ROS) are oxygen-containing molecules which are reactive in
nature and are capable of independent existence in the body. ROS comprise mostly of free …

Role of oxidants in male infertility: rationale, significance, and treatment

A Agarwal, RA Saleh - Urologic Clinics, 2002 - urologic.theclinics.com
Recently, the generation of oxidants, also described as reactive oxygen species (ROS), in
the male reproductive tract has become a real concern because of their potential toxic …

[HTML][HTML] Male infertility and oxidative stress: a focus on the underlying mechanisms

RJ Aitken, JR Drevet, A Moazamian, P Gharagozloo - Antioxidants, 2022 - mdpi.com
Reactive oxygen species (ROS) play a critical role in defining the functional competence of
human spermatozoa. When generated in moderate amounts, ROS promote sperm …

Effect of oxidative stress on male reproduction

A Agarwal, G Virk, C Ong… - The world journal of …, 2014 - synapse.koreamed.org
Infertility affects approximately 15% of couples trying to conceive, and a male factor
contributes to roughly half of these cases. Oxidative stress (OS) has been identified as one …

Functions and effects of reactive oxygen species in male fertility

Z Gibb, RA Griffin, RJ Aitken, GN De Iuliis - Animal reproduction science, 2020 - Elsevier
Reactive oxygen species (ROS) are implicated in all aspects of cellular functions. While the
importance of ROS as signalling molecules is well described, ROS are also associated with …