Drug delivery for Alzheimer's disease using nanotechnology: Challenges and advancements
B Chauhan, S Patel, BG Prajapati, S Singh - Alzheimer's Disease and …, 2024 - Elsevier
Alzheimer's disease (AzD) is the most common type of dementia among older adults, with a
progressive disorder of brain that affect thinking ability, behavior, and memorizing capability …
progressive disorder of brain that affect thinking ability, behavior, and memorizing capability …
[HTML][HTML] Brain-targeted polysorbate 80-emulsified donepezil drug-loaded nanoparticles for neuroprotection
X Tao, S Mao, Q Zhang, H Yu, Y Li, X He… - Nanoscale Research …, 2021 - Springer
Most Alzheimer's disease drugs do not work efficiently because of the blood–brain barrier.
Therefore, we designed a new nanopreparation (PS-DZP-CHP): cholesterol-modified …
Therefore, we designed a new nanopreparation (PS-DZP-CHP): cholesterol-modified …
[HTML][HTML] ApoE-targeting increases the transfer of solid lipid nanoparticles with donepezil cargo across a culture model of the blood–brain barrier
Pharmacological treatment of central nervous system (CNS) disorders is difficult, because
the blood–brain barrier (BBB) restricts the penetration of many drugs into the brain. To solve …
the blood–brain barrier (BBB) restricts the penetration of many drugs into the brain. To solve …
Advanced nanoparticular approaches to combat Alzheimer's disease
R Shah, S Bhattacharya - Pharmaceutical Nanotechnology, 2021 - ingentaconnect.com
Alzheimer's disease (AD) is a neurological disease that affects many of the world's rapidly
ageing population. In the etiology of Alzheimer's disease (AD), the involvement of amyloid β …
ageing population. In the etiology of Alzheimer's disease (AD), the involvement of amyloid β …
[HTML][HTML] Current and future nano-carrier-based approaches in the treatment of Alzheimer's disease
It is a very alarming situation for the globe because 55 million humans are estimated to be
affected by Alzheimer's disease (AD) worldwide, and still it is increasing at the rapid speed …
affected by Alzheimer's disease (AD) worldwide, and still it is increasing at the rapid speed …
Reassembly of native components with donepezil to execute dual-missions in Alzheimer's disease therapy
H Zhang, Y Zhao, M Yu, Z Zhao, P Liu, H Cheng… - Journal of controlled …, 2019 - Elsevier
Alzheimer's disease (AD) is a multifaceted and progressive neurodegenerative disease
characterized by accumulation of amyloid-beta (Aβ) and deficits of acetylcholine …
characterized by accumulation of amyloid-beta (Aβ) and deficits of acetylcholine …
Dual-functional nanoparticles for precise drug delivery to Alzheimer's disease lesions: Targeting mechanisms, pharmacodynamics and safety
X Zheng, C Zhang, Q Guo, X Wan, X Shao, Q Liu… - International journal of …, 2017 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia and is characterized by the
cerebral accumulation of extracellular amyloid plaques. In a previous study, this …
cerebral accumulation of extracellular amyloid plaques. In a previous study, this …
Advancements in nanotherapeutics for Alzheimer's disease: current perspectives
Objectives Considerable progress has been made in the treatment of Alzheimer's disease
(AD), but all available strategies focus on alleviating symptoms rather than curing, which …
(AD), but all available strategies focus on alleviating symptoms rather than curing, which …
Therapeutic strategies and nano-drug delivery applications in management of ageing Alzheimer's disease
In recent years, the incidental rate of neurodegenerative disorders has increased
proportionately with the aging population. Alzheimer's disease (AD) is one of the most …
proportionately with the aging population. Alzheimer's disease (AD) is one of the most …
Neurotherapeutic applications of nanoparticles in Alzheimer's disease
A rapid increase in incidence of neurodegenerative disorders has been observed with the
aging of the population. Alzheimer's disease (AD) is the most common neurodegenerative …
aging of the population. Alzheimer's disease (AD) is the most common neurodegenerative …