Alzheimer's disease and its related dementia types: a review on their management via nanotechnology based therapeutic strategies

PI Siafaka, G Mutlu, NÜ Okur - Current Alzheimer Research, 2020 - ingentaconnect.com
Background: Dementia and its related types such as Alzheimer's disease, vascular dementia
and mixed dementia belong to brain associated diseases, resulting in long-term progressive …

Nanotechnology based delivery systems of drugs currently used to treat alzheimer's disease

N Choubdar, S Avizheh - Nanoscience & Nanotechnology-Asia, 2020 - ingentaconnect.com
Alzheimer's Disease (AD) is one of the most common forms of dementia affecting over 46
million people, according to AD International. Over the past few decades, there has been …

Review of current strategies for delivering Alzheimer's disease drugs across the blood-brain barrier

KH Wong, MK Riaz, Y Xie, X Zhang, Q Liu… - International journal of …, 2019 - mdpi.com
Effective therapy for Alzheimer's disease is a major challenge in the pharmaceutical
sciences. There are six FDA approved drugs (eg, donepezil, memantine) that show some …

Functionalization strategies of polymeric nanoparticles for drug delivery in Alzheimer's disease: Current trends and future perspectives

L La Barbera, E Mauri, M D'Amelio… - Frontiers in neuroscience, 2022 - frontiersin.org
Alzheimer's disease (AD), the most common form of dementia, is a progressive and
multifactorial neurodegenerative disorder whose primary causes are mostly unknown. Due …

Treating Alzheimer's disease using nanoparticle-mediated drug delivery strategies/systems

AK Roghani, RI Garcia, A Roghani, A Reddy… - Ageing Research …, 2024 - Elsevier
The administration of promising medications for the treatment of neurodegenerative
disorders (NDDs), such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's …

Recent advancements in the field of nanotechnology for the delivery of anti-Alzheimer drug in the brain region

M Agrawal, S Saraf, S Saraf… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Brain is supposed to be the most complicated part of the body which is very far
from the reach of drug moieties. The drug entry in to the brain region depends upon various …

Nose-to-Brain Targeted Delivery of Donepezil Hydrochloride via Novel Hyaluronic Acid-Doped Nanotransfersomes for Alzheimer's Disease Mitigation

HF Salem, HM Aboud, MM Abdellatif… - Journal of …, 2024 - Elsevier
Alzheimer's disease is the most serious neurodegenerative disorder characterized by
cognitive and memorial defects alongside deterioration in behavioral, thinking and social …

Donepezil and Embelin loaded Nanostructured lipid carriers for direct brain delivery as an intervention for Alzheimer's disease: Formulation design, Optimization and …

MH Ali, O Alam, A Ali, MU Ali, S Parvez… - Journal of Cluster …, 2024 - Springer
Donepezil hydrochloride (DPL) and Embelin (EMB) loaded Nanostructured Lipid Carriers
(NLCs) have been developed and optimized to achieve optimal drug loading, safer nasal …

Nanotechnology-based drug delivery systems for Alzheimer's disease management: Technical, industrial, and clinical challenges

MM Wen, NS El-Salamouni, WM El-Refaie… - Journal of controlled …, 2017 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease with high prevalence in the
rapidly growing elderly population in the developing world. The currently FDA approved …

Recent advances in nanotechnology-based drug delivery approaches for Alzheimer disease

I Kaur, A Kumar, T Behl, D Setia - Current Drug Targets, 2021 - ingentaconnect.com
One of the most common forms of neurodegenerative disorders, Alzheimer's disease poses
a great threat to patients all over the globe with about 5.7 million cases estimated by the …