Targeted nanoparticles for drug delivery through the blood–brain barrier for Alzheimer's disease

C Roney, P Kulkarni, V Arora, P Antich, F Bonte… - Journal of controlled …, 2005 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia among the elderly,
affecting 5% of Americans over age 65, and 20% over age 80. An excess of senile plaques …

[HTML][HTML] The delivery challenge in neurodegenerative disorders: the nanoparticles role in Alzheimer's disease therapeutics and diagnostics

C De la Torre, V Ceña - Pharmaceutics, 2018 - mdpi.com
Alzheimer's disease (AD) is one of the main causes of disability and dependency among
elderly people. AD is a neurodegenerative disorder characterized by a progressive and …

An update on biomedical application of nanotechnology for Alzheimer's disease diagnosis and therapy

Y Panahi, M Mohammadhosseini, AJN Abadi… - Drug …, 2016 - thieme-connect.com
Approximately 35 million people worldwide suffer from Alzheimer's disease (AD). The
cellular uptake and specific transport of drugs and imaging agents to brain are common …

[HTML][HTML] Recent progress of nanomedicine in the treatment of Alzheimer's disease

L Hu, Y Tao, Y Jiang, F Qin - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Alzheimer's disease (AD) is the most common cause of memory disruption in elderly
subjects, with the prevalence continuing to rise mainly because of the aging world …

Nanomaterials toward the treatment of Alzheimer's disease: Recent advances and future trends

H Zeng, Y Qi, Z Zhang, C Liu, W Peng, Y Zhang - Chinese chemical letters, 2021 - Elsevier
Alzheimer's disease (AD) is a progressive and fatal neurodegenerative condition and the
most prevalent cause of dementia. This disease is characterized by progressive cognitive …

Multifunctional nano-enabled delivery systems in Alzheimer's disease management

C Qian, C Yuan, C Li, H Liu, X Wang - Biomaterials Science, 2020 - pubs.rsc.org
Alzheimer's disease (AD) is the most common neurodegenerative disorder that leads to
cognitive and behavioral impairment. Unfortunately, both effective diagnosis and treatment …

Receptor specific, stimuli responsive and subcellular targeted approaches for effective therapy of Alzheimer: Role of surface engineered nanocarriers

D Gopalan, A Pandey, N Udupa, S Mutalik - Journal of controlled release, 2020 - Elsevier
The present review deals in-depth with the current application of nanotechnology in
targeting the major pathological hallmarks of Alzheimer's disease. This review further …

Acetylcholinesterase inhibitors and nanoparticles on Alzheimer's disease: a review

S Silva, AJ Almeida, N Vale - Journal of Nanoparticle Research, 2021 - Springer
Alzheimer's disease (AD) is a multifactorial neurodegenerative disease clinically
characterized by progressive loss of memory, impairment cognitive function, and …

[HTML][HTML] Nasal delivery of donepezil HCl-loaded hydrogels for the treatment of Alzheimer's disease

S Al Harthi, SE Alavi, MA Radwan, MM El Khatib… - Scientific reports, 2019 - nature.com
This study aims to prepare, characterize and evaluate the pharmacokinetics of liposomal
donepezil HCl (LDH) dispersed into thiolated chitosan hydrogel (TCH) in rabbits. Various …

Biophysical, Biochemical, and Behavioral Implications of ApoE3 Conjugated Donepezil Nanomedicine in a Aβ1–42 Induced Alzheimer's Disease Rat Model

KV Krishna, RN Saha, SK Dubey - ACS Chemical Neuroscience, 2020 - ACS Publications
Alzheimer's disease (AD) is a progressive neurological disorder and is the most common
type of dementia. Amyloid β (Aβ) plaques play an important role in the pathophysiology of …