Neurotherapeutic applications of nanomedicine for treating Alzheimer's disease

B Wilson, KM Geetha - Journal of controlled release, 2020 - Elsevier
Alzheimer's disease (AD) is a progressive, irreversible, fatal brain disease which disturbs
cognitive functions. It affects 35 million people worldwide and the number of people suffering …

Design, development, optimization and characterization of donepezil loaded chitosan nanoparticles for brain targeting to treat Alzheimer's disease

S Md, M Ali, A Bhatnagar, S Baboota… - Science of Advanced …, 2014 - ingentaconnect.com
The purpose of the present study was to investigate the possibility of targeting an anti-
Alzheimer's drug donepezil in the brain using polymeric nanoparticles. The Donepezil …

Brain targeting based nanocarriers loaded with resveratrol in Alzheimer's disease: A review

C Jalili, A Kiani, M Gholami… - IET …, 2023 - Wiley Online Library
Alzheimer's disease (AD) is one of the chief neurological difficulties in the aged population,
identified through dementia, memory disturbance, and reduced cognitive abilities. β‐amyloid …

Nanotechnology approaches for enhanced CNS delivery in treating Alzheimer's disease

MA Arya, MKM Kumar, M Sabitha, KN Menon… - Journal of drug delivery …, 2019 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder affecting the central nervous
system (CNS) characterized by the overproduction of amyloid beta proteins and its inability …

An overview on global trends in nanotechnological approaches for Alzheimer therapy

G Md Ashraf, S Tabrez, NR Jabir… - Current drug …, 2015 - ingentaconnect.com
Despite extensive research for over two decades, the medical science is yet to assign the
exact aetiology and mode of progression of Alzheimer's disease (AD). The modern era of AD …

Nanoparticle-mediated approaches for Alzheimer's disease pathogenesis, diagnosis, and therapeutics

SD Hettiarachchi, Y Zhou, E Seven… - Journal of controlled …, 2019 - Elsevier
Alzheimer's disease (AD) is an irreversible and progressive neurodegenerative disorder
manifested by memory loss and cognitive impairment. Deposition of the amyloid β plaques …

Advancements in the Application of Nanomedicine in Alzheimer's Disease: A Therapeutic Perspective

N Puranik, D Yadav, M Song - International Journal of Molecular Sciences, 2023 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease that affects most
people worldwide. AD is a complex central nervous system disorder. Several drugs have …

Use of biodegradable, chitosan-based nanoparticles in the treatment of Alzheimer's disease

E Manek, F Darvas, GA Petroianu - Molecules, 2020 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects more than
24 million people worldwide and represents an immense medical, social and economic …

Donepezil loaded PLGA nanoparticles, from modified nano-precipitation, an advanced drug delivery system to treat Alzheimer disease

SK Tripathi, B Patel, S Shukla, C Pachouri… - Journal of Physics …, 2021 - iopscience.iop.org
In present works we synthesized Donepezil loaded PLGA nanoparticles (NPs). The
approach of our research group was to prove the improvement of drug transport through the …

[HTML][HTML] Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases

C Saraiva, C Praça, R Ferreira, T Santos… - Journal of controlled …, 2016 - Elsevier
The blood–brain barrier (BBB) is a vital boundary between neural tissue and circulating
blood. The BBB's unique and protective features control brain homeostasis as well as ion …