Recombinant hepatocyte growth factor accelerates cutaneous wound healing in a diabetic mouse model

S Yoshida, K Matsumoto, D Tomioka, K Bessho… - Growth …, 2004 - Taylor & Francis
We examined effects of recombinant hepatocyte growth factor (HGF) on cutaneous wound
healing, using a full-thickness cutaneous excision model in diabetic mice. Topical …

Local administration of hepatocyte growth factor gene enhances the regeneration of dermis in acute incisional wounds

I Ono, T Yamashita, T Hida, HY Jin, Y Ito… - Journal of Surgical …, 2004 - Elsevier
Hepatocyte growth factor (HGF) has a number of biological activities, eg, mitogenic,
motogenic, antiapoptotic, antifibrous, and morphogenic. It also has angiogenic and …

Hepatocyte growth factor regulation: an integral part of why wounds become chronic

K Conway, F Ruge, P Price… - Wound repair and …, 2007 - Wiley Online Library
Hepatocyte growth factor (HGF) is a cytokine known to play multiple roles during the various
stages of wound healing. This study addresses the ongoing key questions regarding the role …

Autocrine production of biologically active hepatocyte growth factor (HGF) by injured human skin

F Nayeri, J Xu, A Abdiu, T Nayeri, D Aili… - Journal of …, 2006 - Elsevier
BACKGROUND: Hepatocyte growth factor (HGF) is a potent regenerative factor involved in
wound healing. Previous studies have shown that mesenchymal cells produce HGF …

Combined administration of basic fibroblast growth factor protein and the hepatocyte growth factor gene enhances the regeneration of dermis in acute incisional …

I Ono, T Yamashita, T Hida, HY Jin, Y Ito… - Wound repair and …, 2004 - Wiley Online Library
Hepatocyte growth factor (HGF) is a ligand for the c‐Met receptor tyrosine kinase. This study
was aimed to characterize the role of the HGF gene combined with basic fibroblast growth …

Effect of human hepatocyte growth factor on promoting wound healing and preventing scar formation by adenovirus-mediated gene transfer

X Ha, Y Li, M Lao, B Yuan, CT Wu - Chinese medical journal, 2003 - mednexus.org
Objective To evaluate the effects of hepatocyte growth factor (HGF) on the prevention of scar
formation and the promotion of wound healing by gene transfer. Methods A total of 12 …

Hepatocyte growth factor; expression, concentration and biological activity in chronic leg ulcers

F Nayeri, H Olsson, C Peterson, T Sundqvist - Journal of dermatological …, 2005 - Elsevier
BACKGROUND:: Hepatocyte growth factor (HGF) is a multifunctional cytokine that is
involved in recovery process after organ injuries. OBJECTIVE:: We studied HGF and the …

Hepatocyte growth factor may accelerate healing in chronic leg ulcers: a pilot study

F Nayeri, T Strömberg, M Larsson, L Brudin… - Journal of …, 2002 - Taylor & Francis
BACKGROUND: Hepatocyte growth factor (HGF) is a heparin-binding protein with
mitogenic, motogenic and morphogenic activities for various cell types. The regenerative …

Synergistic induction of hepatocyte growth factor in human skin fibroblasts by the inflammatory cytokines interleukin-1 and interferon-γ

Y Takami, T Motoki, I Yamamoto, E Gohda - Biochemical and biophysical …, 2005 - Elsevier
Hepatocyte growth factor (HGF) is one of the vital factors for wound healing. HGF expression
markedly increases in wounded skin and is mainly localized in dermal fibroblasts. HGF …

[HTML][HTML] Overexpression of hepatocyte growth factor/scatter factor promotes vascularization and granulation tissue formation in vivo

M Toyoda, H Takayama, N Horiguchi, T Otsuka… - FEBS letters, 2001 - Elsevier
The effect of hepatocyte growth factor/scatter factor (HGF/SF) during wound healing in the
skin was investigated, using HGF/SF-overexpressing transgenic mouse model. Histological …