The population ageing process worldwide is leading to an increasing number of women in
the perimenopausal phase. Many of the perimenopausal symptoms, such as headache …

In this review we systematically summarize the effects of progesterone and synthetic
progestins on neurogenesis, synaptogenesis, myelination and six neurotransmitter systems …

The menopausal transition has been proposed to put women at risk for undesirable
neurological symptoms, including cognitive decline. Previous studies suggest that …

Animal studies have robustly shown hormone related changes in spine density in various
brain areas, specifically the hippocampus. Literature on hormone dependent gray matter …

Women have an increased risk of developing Alzheimer's Dementia (AD) compared to men.
It has been postulated that this risk may be modulated by a reduction in the neuroprotective …

Medial temporal lobe (MTL) atrophy is correlated with risk and severity of Alzheimer disease
(AD) pathology and cognitive decline. Increasing evidence suggest that oestrogens affect …

Profound and multifaceted effects of hormones on the development, maturation and function
of the CNS are well documented. Recent developments in magnetic resonance imagining …

There is increasing evidence from animal and in vitro studies to suggest that estrogen might
have neuroprotective effects, and several plausible physiological mechanisms have been …

Gonadotropin Hormone Releasing Hormone agonists (GnRHa) produce an acute decline in
ovarian hormone production leading to a 'pseudo'menopause. This is therapeutically useful …

Although several functional neuroimaging studies have addressed the relevance of
hormones to cerebral function, none have evaluated the effects of hormones on network …