The prevalence of chronic kidney disease (CKD) has increased and will continue to
increase in the United States and worldwide. This is alarming considering that CKD is an …

Although an elevation of serum uric acid level is often associated with chronic kidney
disease (CKD), it remains controversial whether hyperuricemia per se is a true risk factor for …

Elevated serum uric acid is a marker for decreased renal function, may have a mechanistic
role in the incidence and progression of renal functional decline and likely has a causal role …

Epidemiological studies show that hyperuricemia independently predicts the development of
chronic kidney disease (CKD) in individuals with normal kidney function both in the general …

Abstract Purpose of Review In chronic kidney disease (CKD), plasma uric acid levels are
increased because of the decrease in glomerular filtration rate. However, in addition to CKD …

Hyperuricemia is seen when kidney function declines. Whether elevated uric acid (UA)
levels play a role in the initiation and progression of kidney disease is a subject of a great …

Hyperuricemia predicts the development of chronic kidney disease (CKD) and metabolic
complications, but whether it has a causal role has been controversial. This is especially true …

The relationship between hyperuricemia, gout, and renal disease has been investigated for
several years. From the beginning, kidney disease has been considered a complication of …

Hyperuricemia (elevated serum uric acid) is prevalent, and an important mediator of gout, an
increasingly common condition. In addition, hyperuricemia is associated with metabolic …

Results: The causes for hyperuricemia in overproducers may be either exogenous or
endogenous. CKD has become a global public health problem because of its high …