A genome-wide association study of gout in European populations identified 12 genetic
variants strongly associated with risk of gout, but it is unknown whether these variants are …

Objective The Māori and Pacific (Polynesian) population of Aotearoa New Zealand has a
high prevalence of gout. Our aim was to identify potentially functional missense genetic …

Current evidence suggests heredity and metabolic syndrome contributes to gout
progression. Specifically, the WDR1 and CLNK genes may play a role in gout progression in …

Gout is a common inflammatory arthritis triggered by the presence of monosodium urate
(MSU) crystals in joints and connective tissues. Current evidence suggests that heredity …

Materials and methods: A total of 163 gout patients and 187 normal controls from Minnan
were enrolled in this case-control study. SNPs (rs1165205, rs3733591, rs6855911 …

Gout is usually characterized by recurrent flares of acute inflammatory arthritis and the
crystallization of urate in tissues and joints (Dong et al., 2017). The formation of monosodium …

The relationship between the SLC2A9 (solute carrier family 2, member 9) gene
polymorphisms and gout was still inconsistent among the individual genetic association …

We investigated the interactions of ALPK1 variants and the loci of ABCG2, SLC2A9, and
SLC22A12 on gout risk. We conducted two case–control studies. Participants were recruited …

Background Gout is a common arthritic disease resulting from elevated serum uric acid
(SUA) level. A large meta-analysis including 28,141 individuals identified nine single …

Background Glucose transporter 9 (GLUT9) is a high-capacity/low-affinity urate transporter.
To date, several recent genome-wide association studies (GWAS) and follow-up studies …