Incidence and risk factors for first line anti retroviral treatment failure among Ugandan children attending an urban HIV clinic

R Sebunya, V Musiime, SB Kitaka, G Ndeezi - AIDS research and therapy, 2013 - Springer
Background Early recognition of antiretroviral therapy (ART) failure in resource limited
settings is a challenge given the limited laboratory facilities and trained personnel. This …

Drug resistance is widespread among children who receive long-term antiretroviral treatment at a rural Tanzanian hospital

C Bratholm, A Johannessen, E Naman… - Journal of …, 2010 - academic.oup.com
Objectives To assess long-term virological efficacy and the emergence of drug resistance in
children who receive antiretroviral treatment (ART) in rural Tanzania. Patients and methods …

Antiretroviral drug resistance profiles and response to second-line therapy among HIV type 1-infected Ugandan children

V Musiime, E Kaudha, J Kayiwa, G Mirembe… - AIDS research and …, 2013 - liebertpub.com
We sought to determine the pattern of resistance-associated mutations (RAMs) among HIV-1-
infected children failing first-line antiretroviral therapy (ART) and ascertain their response to …

Predictors of treatment failure and time to detection and switching in HIV-infected Ethiopian children receiving first line anti-retroviral therapy

T Bacha, B Tilahun, A Worku - BMC infectious diseases, 2012 - Springer
Background The emergence of resistance to first line antiretroviral therapy (ART) regimen
leads to the need for more expensive and less tolerable second line drugs. Hence, it is …

Long-term outcome of children receiving antiretroviral treatment in rural South Africa: substantial virologic failure on first-line treatment

RE Barth, HA Tempelman, E Smelt… - The Pediatric …, 2011 - journals.lww.com
Background: Long-term (> 12 months follow-up) virologic data of children receiving
antiretroviral therapy (ART) in Sub-Saharan Africa are limited. Data from rural areas are …

high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy

KCE Sigaloff, J Kayiwa, V Musiime… - AIDS research and …, 2013 - liebertpub.com
HIV-infected children are at high risk of acquiring drug-resistant viruses, which is of
particular concern in settings where antiretroviral drug options are limited. We aimed to …

Magnitude and predictors of antiretroviral treatment failure among HIV‐infected children in Fiche and Kuyu hospitals, Oromia region, Ethiopia: a retrospective cohort …

S Yassin, GB Gebretekle - Pharmacology research & …, 2017 - Wiley Online Library
The objective of the study was to assess the magnitude and predictors of first‐line
antiretroviral treatment failure among HIV‐infected children. A retrospective cohort study was …

Level of viral load and antiretroviral resistance after 6 months of non-nucleoside reverse transcriptase inhibitor first-line treatment in HIV-1-infected children in Mali

D Germanaud, A Derache, M Traore… - Journal of …, 2010 - academic.oup.com
Objectives To evaluate the virological response and to describe the resistance profiles in the
case of failure after 6 months of first-line highly active antiretroviral therapy (HAART) in HIV-1 …

Incidence and risk factors of first-line antiretroviral treatment failure among human immunodeficiency virus-infected children in Amhara regional state, Ethiopia: a …

MM Sisay, TA Ayele, YA Gelaw, AT Tsegaye… - BMJ open, 2018 - bmjopen.bmj.com
Objective This study aimed to assess the incidence and risk factors of treatment failure
among HIV/AIDS-infected children who were on antiretroviral therapy (ART) in Amhara …

Predictors of virologic failure and genotypic resistance mutation patterns in thai children receiving non-nucleoside reverse transcriptase inhibitor–based antiretroviral …

P Jittamala, T Puthanakit, S Chaiinseeard… - The Pediatric …, 2009 - journals.lww.com
Background: Nonnucleoside reverse transcription inhibitor (NNRTI)-based antiretroviral
therapy (ART) has been widely used as a first-line regimen for the treatment of HIV. This …