In recent years there is an increasing interest in the pulmonary delivery of large cohesive
powder doses, ie drugs with a low potency such as antibiotics or drugs with a high potency …

In the last decades, dry powder inhalation has become a very attractive option for pulmonary
drug delivery to treat lung diseases like cystic fibroses and lung infections. In contrast to the …

Importance of the field: The understanding of pulmonary drug delivery and thus its utilization
for medical purposes has remarkably advanced over the last decades. It has been …

This review examines the key issues surrounding the development and preparation of
formulations for dry powder inhalers. The various inhaler devices that are currently available …

The pulmonary route is an interesting route for drug administration, both for effective local
therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the …

Dry powder inhalers (DPIs) are an important and increasingly investigated method of
modern therapy for a growing number of respiratory diseases. DPIs are a promising option …

The pulmonary route of administration has been commonly used for local lung conditions
such as asthma and chronic obstructive pulmonary disease (COPD). Recently, with the …

The efficacy of pharmaceutical aerosols relates to its deposition in the clinically relevant
regions of the lungs, which can be assessed by in vivo lung deposition studies. Dry powder …

Powders for inhalation are traditionally prepared using a destructive micronization process
such as jet milling to reduce the particle size of the drug to 2− 5 μm. The resultant particles …

Pulmonary administration of drugs presents several advantages in the treatment of many
diseases. Considering local and systemic delivery, drug inhalation enables a rapid and …