Those interested in the treatment of asthma have championed the use of dry powder
inhalers to deliver small-molecular-weight drug substances. The major therapeutic …

Inhaled drug delivery 653 Lung anatomy 654 Inhalation aerosols and the importance of
particle size distribution 654 Particle deposition in the airways 655 Formulating and …

Abstract Purpose. Relatively large (> 5 µm) and porous (mass density< 0.4 g/cm 3) particles
present advantages for the delivery of drugs to the lungs, eg, excellent aerosolization …

Recent advances in aerosolization technology have led to renewed interest in pulmonary
delivery of a variety of drugs. Pressurized metered dose inhalers (pMDIs) and dry powder …

Large porous particles are becoming increasingly popular as carriers for pulmonary drug
delivery with both local and systemic applications. These particles have high geometric …

Pulmonary drug delivery is currently the focus of research and development because of its
potential to produce maximum therapeutic benefit to patients by directing the drug straight to …

The inhaled route is increasingly developed to deliver locally acting or systemic therapies,
and rodent models are used to assess tolerance before clinical studies. Endotracheal …

The dry powder inhaler (DPI) has become widely known as a very attractive platform for drug
delivery. Many patients have traditionally used DPIs to treat asthma and chronic obstructive …

The TurbohalerTM is the one multidose reservoir type dry powder inhaler (DPI) with
significant clinical usage but there is little information on the precision of its single dose …

The phenomenon of particle interaction involved in pulmonary drug delivery belongs to a
wide variety of disciplines of particle technology, in particular, fluidization. This paper …