Formulation challenges of powders for the delivery of small molecular weight molecules as aerosols
AJ Hickey - Modified-release drug delivery technology, 2002 - taylorfrancis.com
Those interested in the treatment of asthma have championed the use of dry powder
inhalers to deliver small-molecular-weight drug substances. The major therapeutic …
inhalers to deliver small-molecular-weight drug substances. The major therapeutic …
[PDF][PDF] Pulmonary drug delivery
K Taylor - Any screen. Any time. Anywhere., 2002 - ndl.ethernet.edu.et
Inhaled drug delivery 653 Lung anatomy 654 Inhalation aerosols and the importance of
particle size distribution 654 Particle deposition in the airways 655 Formulating and …
particle size distribution 654 Particle deposition in the airways 655 Formulating and …
Formulation and physical characterization of large porous particles for inhalation
R Vanbever, JD Mintzes, J Wang, J Nice, D Chen… - Pharmaceutical …, 1999 - Springer
Abstract Purpose. Relatively large (> 5 µm) and porous (mass density< 0.4 g/cm 3) particles
present advantages for the delivery of drugs to the lungs, eg, excellent aerosolization …
present advantages for the delivery of drugs to the lungs, eg, excellent aerosolization …
Current therapies and technological advances in aqueous aerosol drug delivery
AB Watts, JT McConville… - Drug development and …, 2008 - Taylor & Francis
Recent advances in aerosolization technology have led to renewed interest in pulmonary
delivery of a variety of drugs. Pressurized metered dose inhalers (pMDIs) and dry powder …
delivery of a variety of drugs. Pressurized metered dose inhalers (pMDIs) and dry powder …
Large porous particles for respiratory drug delivery. Glycine-based formulations
AG Ogienko, EG Bogdanova, NA Trofimov… - European Journal of …, 2017 - Elsevier
Large porous particles are becoming increasingly popular as carriers for pulmonary drug
delivery with both local and systemic applications. These particles have high geometric …
delivery with both local and systemic applications. These particles have high geometric …
[HTML][HTML] Understanding the importance of capsules in dry powder inhalers
F Buttini, E Quarta, C Allegrini, F Lavorini - Pharmaceutics, 2021 - mdpi.com
Pulmonary drug delivery is currently the focus of research and development because of its
potential to produce maximum therapeutic benefit to patients by directing the drug straight to …
potential to produce maximum therapeutic benefit to patients by directing the drug straight to …
Pulmonary delivery of dry powders to rats: tolerability limits of an intra-tracheal administration model
A Guillon, J Montharu, L Vecellio, V Schubnel… - International journal of …, 2012 - Elsevier
The inhaled route is increasingly developed to deliver locally acting or systemic therapies,
and rodent models are used to assess tolerance before clinical studies. Endotracheal …
and rodent models are used to assess tolerance before clinical studies. Endotracheal …
Advancements in dry powder delivery to the lung
YJ Son, JT McConville - Drug development and industrial …, 2008 - Taylor & Francis
The dry powder inhaler (DPI) has become widely known as a very attractive platform for drug
delivery. Many patients have traditionally used DPIs to treat asthma and chronic obstructive …
delivery. Many patients have traditionally used DPIs to treat asthma and chronic obstructive …
Drug delivery characteristics of Bricanyl TurbohalerTM dry powder inhalers
BJ Meakin, JM Cainey, PM Woodcock - International journal of …, 1995 - Elsevier
The TurbohalerTM is the one multidose reservoir type dry powder inhaler (DPI) with
significant clinical usage but there is little information on the precision of its single dose …
significant clinical usage but there is little information on the precision of its single dose …
Dry powder platform for pulmonary drug delivery
DI Daniher, J Zhu - Particuology, 2008 - Elsevier
The phenomenon of particle interaction involved in pulmonary drug delivery belongs to a
wide variety of disciplines of particle technology, in particular, fluidization. This paper …
wide variety of disciplines of particle technology, in particular, fluidization. This paper …