Outcomes of primary membranous nephropathy based on serum anti-phospholipase A2 receptor antibodies and glomerular phospholipase A2 receptor antigen status …

P Yin, J Wang, W Liang, L Zhan, Y Liu, J Lin… - Renal …, 2020 - Taylor & Francis
Introduction Primary membranous nephropathy (PMN) is associated with the anti-
phospholipase A2 receptor (anti-PLA2R) antibody in 70% of cases. Some anti-PLA2R …

[HTML][HTML] Determination of primary versus secondary membranous glomerulopathy utilizing phospholipase A2 receptor staining in renal biopsies

CP Larsen, NC Messias, FG Silva, E Messias… - Modern Pathology, 2013 - Elsevier
Autoantibody formation directed against phospholipase A2 receptor (PLA2R) 1 is the
underlying etiology in most cases of primary membranous glomerulopathy. This new …

Definition of a new cut-off for the anti-phospholipase A2 receptor (PLA2R) autoantibody immunoassay in patients affected by idiopathic membranous nephropathy

M Tampoia, F Migliucci, C Villani, L Abbracciavento… - Journal of …, 2018 - Springer
Autoantibodies against phospholipase A2 receptor (PLA2R) are a sensitive and specific
marker for idiopathic membranous nephropathy (IMN). The aim of our study was to redefine …

[HTML][HTML] Comparison of performance and clinical utility of different methods for detecting anti-PLA2R antibody

T Wang, M Wang, W Yu, H Li, Z Zhao, J Shang - Clinica Chimica Acta, 2023 - Elsevier
Objectives This study aimed to compare the performance of enzyme-linked immunosorbent
assay (ELISA) and magnetic particle chemiluminescence immunoassay (MP-CLIA) for …

Introduction of a novel chimeric active immunization mouse model of PLA2R1-associated membranous nephropathy

NM Tomas, A Schnarre, S Dehde, R Lucas… - Kidney International, 2023 - Elsevier
The phospholipase A2 receptor 1 (PLA2R1) is the major target antigen in patients with
membranous nephropathy (MN), an antibody-mediated autoimmune glomerular disease …

[HTML][HTML] Temporal association between PLA2R antibodies and clinical outcomes in primary membranous nephropathy

R Ramachandran, AK Yadav, V Kumar… - Kidney international …, 2018 - Elsevier
Introduction Autoantibodies to M-type phospholipase A2 receptor (aPLA2R) are seen in two-
thirds of patients with primary membranous nephropathy (PMN) and are associated with …

Renal phospholipase A2 receptor and the clinical features of idiopathic membranous nephropathy

NX Xu, QH Xie, ZX Sun, J Wang, Y Li, L Wang… - Chinese Medical …, 2017 - mednexus.org
Background: According to the renal phospholipase A2 receptor (PLA2R)
immunohistochemistry, idiopathic membranous nephropathy (iMN) could be categorized …

Circulating antibodies against M-type phospholipase A2 receptor and thrombospondin type-1 domain-containing 7A in Chinese patients with membranous …

C Tian, L Li, T Liu, X Qu, Y Qiu - International Urology and Nephrology, 2019 - Springer
Background M-type phospholipase A2 receptor (PLA2R) and thrombospondin type-1
domain-containing 7A (THSD7A) have recently been identified as target antigens for …

[HTML][HTML] Retrospective study: clinicopathological features and prognosis of idiopathic membranous nephropathy with seronegative anti-phospholipase A2 receptor …

W Guo, Y Zhang, C Gao, J Huang, J Li, R Wang… - PeerJ, 2020 - peerj.com
Background To discuss the clinicopathological features and prognosis of patients with
idiopathic membranous nephropathy (IMN) who are serum-negative for the anti-PLA2R …

Identification of a major epitope recognized by PLA2R autoantibodies in primary membranous nephropathy

M Fresquet, TA Jowitt, J Gummadova… - Journal of the …, 2015 - journals.lww.com
Abstract Phospholipase A 2 receptor 1 (PLA2R) is a target autoantigen in 70% of patients
with idiopathic membranous nephropathy. We describe the location of a major epitope in the …