Pilot-Scale Culture of Hypericum Perforatum L. Adventitious Roots in Airlift Bioreactors for the Production of Bioactive Compounds

XH Cui, HN Murthy, KY Paek - Applied biochemistry and biotechnology, 2014 - Springer
Abstract Hypericum perforatum L.(St. John's Wort) is an important medicinal plant which is
widely used in the treatment for depression and irritable bowel syndrome. It is also used as a …

Production of adventitious root biomass and secondary metabolites of Hypericum perforatum L. in a balloon type airlift reactor

XH Cui, HN Murthy, YX Jin, YH Yim, JY Kim… - Bioresource …, 2011 - Elsevier
The effects of inoculum density, aeration volume and culture period on accumulation of
biomass and secondary metabolites in adventitious roots of Hypericum perforatum in …

Production of Adventitious Root Biomass and Bioactive Compounds from Hypericum perforatum L. Through Large Scale Bioreactor Cultures

XH Cui, HN Murthy, KY Paek - … of biomass and bioactive compounds using …, 2014 - Springer
Abstract Hypericum perforatum L.(St. John's wort) is a traditional medicinal plant with
antidepressive and woundhealing properties. It contains a lot of constituents with …

Production of adventitious roots and secondary metabolites by Hypericum perforatum L. in a bioreactor

XH Cui, D Chakrabarty, EJ Lee, KY Paek - Bioresource technology, 2010 - Elsevier
We investigated the effects of different concentrations of auxin and auxin/cytokinin
combinations, inoculum sizes and Murashige and Skoog (MS) medium dilutions on biomass …

Development of a low-cost disposable bioreactor for pilot scale production of Hypericum perforatum L. adventitious roots

A Sobhani, M Khanahmadi, A Jalali, K Moradi… - Industrial Crops and …, 2021 - Elsevier
Bioreactors are widely used for industrial production of therapeutic products. In this study, a
disposable bubble column bioreactor made from flexible plastic films and cheap accessories …

[HTML][HTML] Different Types of Hypericum perforatum cvs. (Elixir, Helos, Topas) In Vitro Cultures: A Rich Source of Bioactive Metabolites and Biological Activities of …

I Kwiecień, N Miceli, E Kędzia, E Cavò, MF Taviano… - Molecules, 2023 - mdpi.com
Microshoot agitated and bioreactor cultures (PlantForm bioreactors) of three Hypericum
perforatum cultivars (Elixir, Helos, Topas) were maintained in four variants of Murashige and …

In vitro production and chemical characterization of St. John's wort (Hypericum perforatum L. cv 'New Stem')

SMA Zobayed, SJ Murch, HPV Rupasinghe… - Plant Science, 2004 - Elsevier
Hypericum perforatum L.(St. John's wort) is a traditional medicinal plant that has been used
for the treatment of neurological disorders and depression. To investigate a large-scale in …

Several factors affecting hypericin production of Hypericum perforatum during adventitious root culture in airlift bioreactors

SQ Wu, XK Yu, ML Lian, SY Park, XC Piao - Acta physiologiae plantarum, 2014 - Springer
Hypericum perforatum L. is a traditional medicinal plant for the treatment of depression and
wound healing, and hypericin is one of the main effective active substances. To optimize the …

Adventitious root suspension cultures of Hypericum perforatum: effect of nitrogen source on production of biomass and secondary metabolites

XH Cui, HN Murthy, CH Wu, KY Paek - In Vitro Cellular & Developmental …, 2010 - Springer
The present study investigated the effect of nitrogen source (NH 4+; NO 3−) at different
concentrations on the accumulation of biomass and secondary metabolites in adventitious …

Recent advances in tissue culture and secondary metabolite production in Hypericum perforatum L.

Shasmita, S Behera, P Mishra, M Samal… - Plant Cell, Tissue and …, 2023 - Springer
Hypericum perforatum L., commonly known as St. John's wort is an important medicinal
plant, belonging to family Hypericaceae. Among all species of Hypericum, H. perforatum is …