Effect of a liberal versus restrictive transfusion strategy on mortality in patients with moderate to severe head injury

LA McIntyre, DA Fergusson, JS Hutchison… - Neurocritical care, 2006 - Springer
Objective To compare a restrictive versus a liberal transfusion strategy in patients with
moderate to severe closed head injury following multiple trauma in 13 Canadian intensive …

[HTML][HTML] Aggressive red blood cell transfusion: no association with improved outcomes for victims of isolated traumatic brain injury

ME George, DE Skarda, CR Watts, HD Pham… - Neurocritical care, 2008 - Springer
Background Clinical studies have caused blood transfusion practices in critically ill patients
to become more conservative in the last decade. However, few studies have focused on …

[HTML][HTML] Transfusion practices for acute traumatic brain injury: a survey of physicians at US trauma centers

MJ Sena, RM Rivers, JP Muizelaar, FD Battistella… - Intensive care …, 2009 - Springer
Purpose To determine whether physician specialty influences transfusion threshold in
patients with acute severe traumatic brain injury (TBI). Methods We surveyed transfusion …

Retrospective evaluation of anemia and transfusion in traumatic brain injury

AP Carlson, CR Schermer, SW Lu - Journal of Trauma and Acute …, 2006 - journals.lww.com
Background: Despite clear evidence in critical care that blood transfusion has an adverse
impact on outcome, neurosurgical textbooks still recommend transfusion of patients with …

The effect of anemia and blood transfusions on mortality in closed head injury patients

TM Duane, J Mayglothling, R Grandhi, N Warrier… - Journal of Surgical …, 2008 - Elsevier
BACKGROUND: The purpose of this study was to determine if anemia in isolated head
trauma patients results in a higher mortality rate that would justify a more liberal use of blood …

The association of blood component use ratios with the survival of massively transfused trauma patients with and without severe brain injury

PC Spinella, CE Wade, LH Blackbourne… - Journal of Trauma …, 2011 - journals.lww.com
Background: The effect of blood component ratios on the survival of patients with traumatic
brain injury (TBI) has not been studied. Methods: A database of patients transfused in the …

Transfusions and long-term functional outcomes in traumatic brain injury

MA Warner, T O'Keeffe, P Bhavsar, R Shringer… - Journal of …, 2010 - thejns.org
Object In this paper, the authors' goal was to examine the relationship between transfusion
and long-term functional outcomes in moderately anemic patients (lowest hematocrit [HCT] …

The effect of red blood cell transfusion on cerebral oxygenation and metabolism after severe traumatic brain injury

DA Zygun, J Nortje, PJ Hutchinson, I Timofeev… - Critical care …, 2009 - journals.lww.com
Objective: There is evidence to suggest that anemia after severe traumatic brain injury (sTBI)
is detrimental. However, there is a paucity of evidence supporting the use of transfusion of …

Is a restrictive transfusion strategy safe for resuscitated and critically ill trauma patients?

L McIntyre, PC Hebert, G Wells… - Journal of Trauma …, 2004 - journals.lww.com
Background: An analysis from the prospective multicenter randomized controlled trial
(Transfusion Requirements in Critical Care Trial) compared the use of restrictive and liberal …

Transfusion practices in traumatic brain injury

JM East, J Viau-Lapointe… - Current Opinion in …, 2018 - journals.lww.com
Currently, there is insufficient evidence to make strong recommendations regarding which
hemoglobin threshold to use as a transfusion trigger in critically-ill patients with TBI. There is …