CEACAM1 impedes thyroid cancer growth but promotes invasiveness: a putative mechanism for early metastases

W Liu, W Wei, D Winer, AM Bamberger, C Bamberger… - Oncogene, 2007 - nature.com
CEACAM1, also known as biliary glycoprotein (BGP), CD66a, pp120 and C-CAM1, is a
member of the CEA immunoglobulin superfamily. CEACAM1 is a putative tumor suppressor …

CEACAM6 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition via PI3K/AKT signaling pathway

M Zang, B Zhang, Y Zhang, J Li, L Su, Z Zhu, Q Gu… - PloS one, 2014 - journals.plos.org
Overexpressed CEACAM6 in tumor tissues plays important roles in invasion, metastasis and
anoikis resistance in a variety of human cancers. We recently reported that CEACAM6 …

Soluble isoforms of CEACAM1 containing the A2 domain: increased serum levels in patients with obstructive jaundice and differences in 3‐fucosyl‐N‐acetyl …

L Draberova, H Černá, H Brodska, M Boubelik… - …, 2000 - Wiley Online Library
CEACAM1 (biliary glycoprotein or CD66a) is a member of the carcinoembryonic antigen
(CEA) subgroup of the CEA family. Eleven RNA isoforms derived from the splicing of a …

Computational Analysis of Isoform‐Specific Signal Regulation by CEACAM1—A Cell Adhesion Molecule Expressed in PC12 Cells

B Öbrink, H Sawa, I Scheffrahn… - Annals of the New …, 2002 - Wiley Online Library
CEACAM1 is a signal‐regulating, homophilic cell adhesion receptor system expressed in
epithelia, vessel endothelia, and leukocytes. Here, we demonstrate that CEACAM1 is …

Signal transduction by the CEACAM1 tumor suppressor: phosphorylation of serine 503 is required for growth-inhibitory activity

VT Estrera, DT Chen, W Luo, DC Hixson… - Journal of Biological …, 2001 - ASBMB
CEACAM1 is a cell-cell adhesion molecule that mediates homophilic cell adhesion. In
addition, CEACAM1 was also shown to suppress the growth of prostate, breast, and colon …

The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction

L Chen, Z Chen, K Baker, EM Halvorsen, AP da Cunha… - Immunity, 2012 - cell.com
Carcinoembryonic antigen cell adhesion molecule like I (CEACAM1) is expressed on
activated T cells and signals through either a long (L) cytoplasmic tail containing immune …

Regulation of CEACAM family members by IBD-associated triggers in intestinal epithelial cells, their correlation to inflammation and relevance to IBD pathogenesis

G Saiz-Gonzalo, N Hanrahan, V Rossini… - Frontiers in …, 2021 - frontiersin.org
Carcinoembryogenic antigen cellular adhesion molecules (CEACAMs) are intercellular
adhesion molecules highly expressed in intestinal epithelial cells. CEACAM1,-3,-5,-6,-7 are …

[HTML][HTML] The expression and modulation of CEACAM1 and tumor cell transformation

V Fiori, M Magnani… - Annali dell'Istituto superiore …, 2012 - SciELO Public Health
BACKGROUND: In this review, we focus our discussion on one class of carcinoembryonic
antigen-related cell adhesion molecules, Carcinoembryonic antigen-related cell adhesion …

T cell-mediated elimination of cancer cells by blocking CEACAM6–CEACAM1 interaction

J Pinkert, HH Boehm, M Trautwein, WD Doecke… - …, 2022 - Taylor & Francis
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), a cell surface
receptor, is expressed on normal epithelial tissue and highly expressed in cancers of high …

[HTML][HTML] Characterizing CEACAM5 interaction with CD8α and CD1d in intestinal homeostasis

G Roda, X Jianyu, MS Park, L DeMarte… - Mucosal …, 2014 - Elsevier
Normal intestinal epithelial cells (IECs) could act as non-professional antigen-presenting
cells, selectively activating CD8+-suppressor T cells. An epithelial cell surface glycoprotein …