The role of biliary carcinoembryonic antigen-related cellular adhesion molecule 6 (CEACAM6) as a biomarker in cholangiocarcinoma

JB Rose, C Correa-Gallego, Y Li, J Nelson, A Alseidi… - PLoS …, 2016 - journals.plos.org
Objective The aim of the present study is to determine if CEACAM6 can be detected in the
bile of patients with biliary cancer and can serve as a diagnostic biomarker for …

CEACAM1 and the regulation of mucosal inflammation

T Nagaishi, Z Chen, L Chen, H Iijima, A Nakajima… - Mucosal …, 2008 - nature.com
Inflammatory bowel disease (IBD) is characterized by unrestrained T-cell activation that
results in the production of a variety of inflammatory cytokines and other mediators …

Leptin resistance contributes to obesity in mice with null mutation of carcinoembryonic antigen-related cell adhesion molecule 1

G Heinrich, L Russo, TR Castaneda, V Pfeiffer… - Journal of Biological …, 2016 - ASBMB
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) promotes hepatic
insulin clearance. Consistently, mice with null mutation of Ceacam1 (Cc1−/−) exhibit …

The CEACAM1-mediated apoptosis pathway is activated by CEA and triggers dual cleavage of CEACAM1

S Nittka, C Böhm, H Zentgraf, M Neumaier - Oncogene, 2008 - nature.com
Marked reduction in apoptosis is a hallmark of early colon tumour growth and the vast
majority of these tumours exhibit a loss of expression of the glycoprotein carcinoembryonic …

CEACAM6 gene expression in intrahepatic cholangiocarcinoma

K Ieta, F Tanaka, T Utsunomiya, H Kuwano… - British journal of …, 2006 - nature.com
The purpose of this study was to investigate the clinicopathological and biological
significance of human carcinoembryonic antigen-related cell adhesion molecule 6 …

CEACAM1 isoforms with different cytoplasmic domains show different localization, organization and adhesive properties in polarized epithelial cells

U Sundberg, B Öbrink - Journal of Cell Science, 2002 - journals.biologists.com
CEACAM1 is a signaling cell adhesion molecule expressed in epithelia, vessel endothelia
and leukocytes. It is expressed as two major isoforms with different cytoplasmic domains …

On the role of CEACAM1 in cancer

B Öbrink - Lung Cancer, 2008 - lungcancerjournal.info
In the present issue of Lung Cancer, Dango et al. report that increased CEACAM1
expression in the tumor cells and increased microvascular density (MVD) in the vicinity of …

[HTML][HTML] CEACAM6 is a prognostic biomarker and potential therapeutic target for gastric carcinoma

GQ Ru, Y Han, W Wang, Y Chen, HJ Wang, WJ Xu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
This study aims to investigate the prognostic power of carcinoembryonic antigen-related cell
adhesion molecule 6 (CEACAM6) in gastric cancer (GC) and its potential role in cancer …

Deregulation of the CEACAM expression pattern causes undifferentiated cell growth in human lung adenocarcinoma cells

BB Singer, I Scheffrahn, R Kammerer, N Suttorp… - PloS one, 2010 - journals.plos.org
CEACAM1, CEA/CEACAM5, and CEACAM6 are cell adhesion molecules (CAMs) of the
carcinoembryonic antigen (CEA) family that have been shown to be deregulated in lung …

Novel protein isoforms of carcinoembryonic antigen are secreted from pancreatic, gastric and colorectal cancer cells

K Hatakeyama, K Wakabayashi-Nakao, K Ohshima… - BMC research …, 2013 - Springer
Background Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is an
oncofetal cell surface glycoprotein. Because of its high expression in cancer cells and …