Role of CEACAM1 isoforms in an in vivo model of mammary morphogenesis: mutational analysis of the cytoplasmic domain of CEACAM1-4S reveals key residues …

S Yokoyama, CJ Chen, T Nguyen, JE Shively - Oncogene, 2007 - nature.com
CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1) is a type I
transmembrane glycoprotein expressed in epithelial cells with three or four extracellular …

CEACAM1 and the regulation of mucosal inflammation

T Nagaishi, Z Chen, L Chen, H Iijima, A Nakajima… - Mucosal …, 2008 - nature.com
Inflammatory bowel disease (IBD) is characterized by unrestrained T-cell activation that
results in the production of a variety of inflammatory cytokines and other mediators …

Overexpression of CEACAM6 promotes migration and invasion of oestrogen-deprived breast cancer cells

JS Lewis-Wambi, HE Cunliffe, HR Kim, AL Willis… - European journal of …, 2008 - Elsevier
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) is an intercellular
adhesion molecule that is overexpressed in a wide variety of human cancers, including …

Genetic alterations and expression pattern of CEACAM1 in colorectal adenomas and cancers

JH Song, Z Cao, JH Yoon, SW Nam, SY Kim… - Pathology & Oncology …, 2011 - Springer
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is expressed on
epithelial cells throughout the intestinal tract and is a negative regulator of tumor cell growth …

Emerging role and targeting of carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) in human malignancies

B Johnson, D Mahadevan - Clinical cancer drugs, 2015 - ingentaconnect.com
Background: Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) is a
member of the CEA family of cell adhesion proteins that belong to the immunoglobulin …

The CEACAM1 N-terminal Ig domain mediates cis-and trans-binding and is essential for allosteric rearrangements of CEACAM1 microclusters

E Klaile, O Vorontsova, K Sigmundsson… - Journal of cell …, 2009 - rupress.org
Cell adhesion molecules (CAMs) sense the extracellular microenvironment and transmit
signals to the intracellular compartment. In this investigation, we addressed the mechanism …

CEACAM5 stimulates the progression of non-small-cell lung cancer by promoting cell proliferation and migration

X Zhang, X Han, P Zuo, X Zhang… - Journal of International …, 2020 - journals.sagepub.com
Objective To detect the expression of CEA-related cell adhesion molecule 5 (CEACAM5) in
non-small-cell lung cancer (NSCLC) and explore its function in the progression and …

Mechanism of glucose intolerance in mice with dominant negative mutation of CEACAM1

SY Park, YR Cho, HJ Kim, EG Hong… - American Journal …, 2006 - journals.physiology.org
Mice with liver-specific overexpression of dominant negative phosphorylation-defective
S503A-CEACAM1 mutant (L-SACC1) developed chronic hyperinsulinemia resulting from …

Role of CEACAM1 as a regulator of T cells

T Nagaishi, H Iijima, A Nakajima… - Annals of the New …, 2006 - Wiley Online Library
A major inmmunological attribute of inflammatory bowel disease (IBD) is the presence of
unrestrained activation of T cells that produce a variety of inflammatory cytokines and other …

Clinical and experimental studies regarding the expression and diagnostic value of carcinoembryonic antigen-related cell adhesion molecule 1 in non-small-cell lung …

M Zhou, Y Du, Y Liu, Y Wang, Y He, C Yang, W Wang… - BMC cancer, 2013 - Springer
Background Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is a
multifunctional Ig-like cell adhesion molecule that has a wide range of biological functions …