Cellular analysis of host cell infection by different developmental stages of Trypanosoma cruzi
L Florencio-Martínez, C Márquez-Dueñas… - Experimental …, 2010 - Elsevier
Trypanosoma cruzi is an obligate intracellular parasite that infects phagocytic and non-
phagocytic mammalian cells by a complex process that appears to involve several discrete …
phagocytic mammalian cells by a complex process that appears to involve several discrete …
Intracellular DNA replication and differentiation of Trypanosoma cruzi is asynchronous within individual host cells in vivo at all stages of infection
Investigations into intracellular replication and differentiation of Trypanosoma cruzi within
the mammalian host have been restricted by limitations in our ability to detect parasitized …
the mammalian host have been restricted by limitations in our ability to detect parasitized …
Trypanosoma cruzi: single cell live imaging inside infected tissues
Although imaging the live Trypanosoma cruzi parasite is a routine technique in most
laboratories, identification of the parasite in infected tissues and organs has been hindered …
laboratories, identification of the parasite in infected tissues and organs has been hindered …
Exploiting Genetically Modified Dual-Reporter Strains to Monitor Experimental Trypanosoma cruzi Infections and Host-Parasite Interactions
MC Taylor, AF Francisco, S Jayawardhana… - T. cruzi Infection …, 2019 - Springer
Trypanosoma cruzi is the causative agent of Chagas disease, the most important parasitic
infection in Latin America. Despite a global research effort, there have been no significant …
infection in Latin America. Despite a global research effort, there have been no significant …
Transient transfection and expression of foreign and endogenous genes in the intracellular stages of Trypanosoma cruzi
The capacity for rapid localization of epitope-tagged or fluorescent fusion proteins in cells is
an important tool for biological discovery and functional analysis. For Trypanosoma cruzi …
an important tool for biological discovery and functional analysis. For Trypanosoma cruzi …
Bioluminescent: fluorescent Trypanosoma cruzi reporter strains as tools for exploring Chagas disease pathogenesis and drug activity
Chagas disease results from infection with the trypanosomatid parasite Trypanosoma cruzi.
Progress in developing new drugs has been hampered by the long term and complex nature …
Progress in developing new drugs has been hampered by the long term and complex nature …
A panel of phenotypically and genotypically diverse bioluminescent:fluorescent Trypanosoma cruzi strains as a resource for Chagas disease research
F Olmo, S Jayawardhana, AA Khan… - PLOS Neglected …, 2024 - journals.plos.org
Chagas disease is caused by Trypanosoma cruzi, a protozoan parasite that displays
considerable genetic diversity. Infections result in a range of pathological outcomes, and …
considerable genetic diversity. Infections result in a range of pathological outcomes, and …
Establishment of larval zebrafish as an animal model to investigate Trypanosoma cruzi motility in vivo
V Akle, N Agudelo-Dueñas… - JoVE (Journal of …, 2017 - jove.com
Chagas disease is a parasitic infection caused by Trypanosoma cruzi, whose motility is not
only important for localization, but also for cellular binding and invasion. Current animal …
only important for localization, but also for cellular binding and invasion. Current animal …
In Vivo Analysis of Trypanosoma cruzi Persistence Foci at Single-Cell Resolution
AI Ward, MD Lewis, AA Khan, CJ McCann… - Mbio, 2020 - Am Soc Microbiol
Infections with Trypanosoma cruzi are usually lifelong despite generating a strong adaptive
immune response. Identifying the sites of parasite persistence is therefore crucial to …
immune response. Identifying the sites of parasite persistence is therefore crucial to …
[HTML][HTML] In vivo imaging of trypanosomes for a better assessment of host–parasite relationships and drug efficacy
S Goyard, PL Dutra, P Deolindo, D Autheman… - Parasitology …, 2014 - Elsevier
The advances in microscopy combined to the invaluable progress carried by the utilization
of molecular, immunological or immunochemical markers and the implementation of more …
of molecular, immunological or immunochemical markers and the implementation of more …
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