A role for granulocyte and monocyte apheresis in the treatment of rheumatoid arthritis

N Kashiwagi, I Hirata, R Kasukawa - Therapeutic Apheresis, 1998 - Wiley Online Library
Rheumatoid arthritis (RA) is an inflammatory condition, the etiology of which is not well
understood. Recent reports indicate a major role of granulocytes in the pathogenesis of RA; …

Granulocyte and monocyte apheresis suppresses symptoms of rheumatoid arthritis: a pilot study

M Nagashima, S Yoshino, H Tanaka, N Yoshida… - Rheumatology …, 1998 - Springer
To investigate if granulocyte and monocyte apheresis mitigates the symptoms of rheumatoid
arthritis (RA), and influences production of panmyelocytes (CD15+ CD16–cells) at the bone …

Granulocytapheresis in the treatment of patients with rheumatoid arthritis

M Ohara, AR Saniabadi, S Kokuma, I Hirata… - Artificial …, 1997 - Wiley Online Library
The G‐1 column is an extracorporeal type granulocytapheresis device packed with 220 g
cellulose acetate beads to which granulocytes and monocytes specifically adhere. A total of …

Anti-inflammatory effect of granulocyte and monocyte adsorption apheresis in a rabbit model of immune arthritis

N Kashiwagi, M Nakano, AR Saniabadi, M Adachi… - Inflammation, 2002 - Springer
In active rheumatoid arthritis, large numbers of granulocytes and macrophages are found in
the inflamed joints. These leucocytes can promote inflammation and tissue injury by …

Evaluation of filtration leucocytapheresis for use in the treatment of patients with rheumatoid arthritis

Y Ueki, S Yamasaki, Y Kanamoto, T Kawazu… - …, 2000 - academic.oup.com
Objectives. To evaluate the efficacy of filtration leucocytapheresis (LCP) for rheumatoid
arthritis (RA). Methods. LCP was carried out three times, with 1 week separating each …

Adsorptive granulocyte/monocyte apheresis for the treatment of refractory rheumatoid arthritis: an open pilot multicentre trial

R Sanmarti, S Marsal, J Valverde, E Casado… - …, 2005 - academic.oup.com
Objective. To assess the efficacy and safety of adsorptive granulocyte and monocyte
apheresis (GCAP) in patients with refractory rheumatoid arthritis (RA). Methods. Patients …

Improvement in rheumatoid arthritis following application of an extracorporeal granulotrap column, G-1

J Fujimori, S Yoshino, M Koiwa, H Hirai… - Rheumatology …, 1996 - Springer
Patients with rheumatoid arthritis (RA) showed significantly (P< 0.01) increased numbers of
granulocytes in their peripheral blood compared with normal donors and patients with …

Filtration leukocytapheresis therapy in rheumatoid arthritis: a randomized, double‐blind, placebo‐controlled trial

T Hidaka, K Suzuki, Y Matsuki… - … : Official Journal of …, 1999 - Wiley Online Library
Objective To determine the efficacy and safety of filtration leukocytapheresis (LCP) for the
treatment of rheumatoid arthritis (RA). Methods Twenty‐five patients with drug‐resistant RA …

[PDF][PDF] A multicenter study of leukocytapheresis in rheumatoid arthritis

Y Ueki, A Sagawa, K Tanimura, A Yamada… - Clinical & …, 2007 - researchgate.net
CLIN AND EXP RHEUM 25/6 Page 1 Clinical and Experimental Rheumatology 2007; 25:
810-816. A multicenter study of leukocytapheresis in rheumatoid arthritis Y. Ueki1, A. Sagawa2 …

Dynamic changes in cytokine levels in serum and synovial fluid following filtration leukocytapheresis therapy in patients with rheumatoid arthritis

T Hidaka, K Suzuki, M Kawakami… - Journal of Clinical …, 2001 - Wiley Online Library
We attempted to determine whether various cytokine levels in the serum and synovial fluid
(SF) of rheumatoid arthritis (RA) patients are influenced by the performance of filtration …