A volatile biomarker in breath predicts lung cancer and pulmonary nodules

M Phillips, TL Bauer, HI Pass - Journal of Breath Research, 2019 - iopscience.iop.org
Background: previous studies have reported volatile organic compounds (VOCs) in the
breath as apparent biomarkers of lung cancer. We tested the hypothesis that a robust breath …

Blinded validation of breath biomarkers of lung cancer, a potential ancillary to chest CT screening

M Phillips, TL Bauer, RN Cataneo, C Lebauer… - PLoS …, 2015 - journals.plos.org
Background Breath volatile organic compounds (VOCs) have been reported as biomarkers
of lung cancer, but it is not known if biomarkers identified in one group can identify disease …

Prediction of lung cancer using volatile biomarkers in breath

M Phillips, N Altorki, JHM Austin… - Cancer …, 2007 - content.iospress.com
Background: Normal metabolism generates several volatile organic compounds (VOCs) that
are excreted in the breath (eg alkanes). In patients with lung cancer, induction of high-risk …

Exploring volatile organic compounds in breath for high-accuracy prediction of lung cancer

PH Tsou, ZL Lin, YC Pan, HC Yang, CJ Chang… - Cancers, 2021 - mdpi.com
Simple Summary Human-exhaled volatile organic compounds (VOCs) can be altered by
lung cancer and become identifiable biomarkers. We used selected ion flow tube mass …

Exhaled breath volatile organic compound biomarkers in lung cancer

PJ Mazzone - Journal of Breath Research, 2012 - iopscience.iop.org
There has been an increased focus on the development of non-invasive biomarkers capable
of accurately identifying lung cancer early in its course and characterizing the nature of the …

Detection of lung cancer with volatile markers in the breath

M Phillips, RN Cataneo, ARC Cummin, AJ Gagliardi… - Chest, 2003 - Elsevier
Study objectives To evaluate volatile organic compounds (VOCs) in the breath as tumor
markers in lung cancer. Alkanes and monomethylated alkanes are oxidative stress products …

Bronchoscopically obtained volatile biomarkers in lung cancer

K Darwiche, JI Baumbach, U Sommerwerck… - Lung, 2011 - Springer
Background The exhaled breath of lung cancer patients contains volatile organic
compounds (VOCs) that differ from those in healthy individuals. These VOCs can be …

Critical review of volatile organic compound analysis in breath and in vitro cell culture for detection of lung cancer

Z Jia, A Patra, VK Kutty, T Venkatesan - Metabolites, 2019 - mdpi.com
Breath analysis is a promising technique for lung cancer screening. Despite the rapid
development of breathomics in the last four decades, no consistent, robust, and validated …

Analyses of lung cancer-derived volatiles in exhaled breath and in vitro models

F Choueiry, A Barham, J Zhu - Experimental Biology and …, 2022 - journals.sagepub.com
Lung cancer is one of the leading causes of cancer incidence and cancer-related deaths in
the world. Early diagnosis of pulmonary tumors results in improved survival compared to …

Volatile organic compounds in exhaled breath as fingerprints of lung cancer, asthma and COPD

IA Ratiu, T Ligor, V Bocos-Bintintan… - Journal of clinical …, 2020 - mdpi.com
Lung cancer, chronic obstructive pulmonary disease (COPD) and asthma are inflammatory
diseases that have risen worldwide, posing a major public health issue, encompassing not …