Liposomes, which are biodegradable and essentially non-toxic vehicles, can encapsulate
both hydrophilic and hydrophobic materials, and are utilized as drug carriers in drug delivery …

Inhibition of the rapid uptake of liposomes by the reticulo-endothelial system (RES) and
reduction of the rate of drug leakage have resulted in long-circulating liposomal drug …

The pharmacokinetics and biodistribution of liposome-encapsulated drugs are controlled by
the interplay of two variables: the rate of plasma clearance of the liposome carrier, and the …

As drug carriers, liposomes have great potential in that selective targeting and release rate
control of drugs can be performed by appropriate modifications to the carrier itself, without …

Liposomes are the most widely used nanocarrier systems in medicine. Common strategies
for tumor-specific drug delivery using liposomes include the passive accumulation of …

Liposomes have raised considerable interest as drug carriers in cancer chemotherapy
(Gregoriadis, 1995) given their ability to control the release rate and alter the biodistribution …

Nanoscale drug delivery systems including liposomes, polymers, and other nanoparticles
provide potential solutions for improved cancer therapeutics. Of these drug delivery systems …

Coating of liposomes with polyethylene-glycol (PEG) by incorporation in the liposome
bilayer of PEG-derivatized lipids results in inhibition of liposome uptake by the reticulo …

Considerable adverse side effects and cytotoxicity of highly potent drugs for healthy tissue
require the development of novel drug delivery systems to improve pharmacokinetics and …

Chemotherapy is a modality of cancer therapy that needs much improvement. Development
of a new chemical entity is very costly and time consuming, but improvements in delivery of …