Blocking of type 1 angiotensin II receptor inhibits T-lymphocyte activation and IL-2 production

S Tawinwung, N Petpiroon, P Chanvorachote - in vivo, 2018 - iv.iiarjournals.org
Background/Aim: Novel information on the role of endogenous compounds in regulating
physiological and pathological process are of interest, as it may lead to the development of …

Angiotensin-(1–7) enhances angiotensin II induced phosphorylation of ERK1/2 in mouse bone marrow-derived dendritic cells

W Nie, H Yan, S Li, Y Zhang, F Yu, W Zhu, F Fan… - Molecular …, 2009 - Elsevier
It is well known that angiotensin-(1–7)(Ang-(1–7)) counterbalances vasoconstrictive and
proliferative functions of angiotensin II (Ang II), some of those actions are via inhibition of …

[HTML][HTML] AT1R blockade reduces IFN-γ production in lymphocytes in vivo and in vitro

JA Weidanz, LM Jacobson, RJ Muehrer, A Djamali… - Kidney international, 2005 - Elsevier
AT 1 R blockade reduces IFN-γ production in lymphocytes in vivo and in vitro. Background
Type 1 angiotensin II (Ang II) receptor (AT 1 R) signaling induces proinflammatory …

Angiotensin II upregulates renin–angiotensin system in human isolated T lymphocytes

M Coppo, M Boddi, M Bandinelli, D Degl'Innocenti… - Regulatory peptides, 2008 - Elsevier
This study was aimed at investigating the effects of Angiotensin (Ang) II stimulation on T
lymphocytes mRNA expression of angiotensinogen (AGTN), angiotensin-converting enzyme …

Role of angiotensin II type 1 receptor in angiotensin II-induced cytokine production in macrophages

F Guo, XL Chen, F Wang, X Liang, YX Sun… - Journal of interferon & …, 2011 - liebertpub.com
This study was aimed to investigate the regulatory effects of angiotensin II (Ang II) on the
expression of Ang II type 1 (AT1) receptor and to characterize the mechanism underlying …

AT1 receptor-mediated angiotensin II activation and chemotaxis of T lymphocytes

JL Silva-Filho, MC Souza, M das Graças Henriques… - Molecular …, 2011 - Elsevier
Angiotensin II (Ang II), a central renin–angiotensin system (RAS) effector molecule, and its
receptors, AT1 and AT2, have been shown to be involved in the inflammatory aspects of …

Angiotensin II enhances the proliferation of Natural Killer/T-cell lymphoma cells via activating PI3K/Akt signaling pathway

GH Zhang, FA Miao, JG Xu, Y Zhang - Bioscience Reports, 2020 - portlandpress.com
The present study was to determine the roles of Angiotensin (Ang) II in the growth of
lymphoma in nude mice and the proliferation and viability of the human Natural Killer/T …

Angiotensin II Type-2 receptors modulate inflammation through signal transducer and activator of transcription proteins 3 phosphorylation and TNFα production

PM Abadir, JD Walston, RM Carey… - Journal of Interferon & …, 2011 - liebertpub.com
Angiotensin subtype-1 receptor (AT1R) influences inflammatory processes through
enhancing signal transducer and activator of transcription proteins 3 (STAT3) signal …

Changes of gene expression profiles in macrophages stimulated by angiotensin II—Angiotensin II induces MCP-2 through AT1-receptor

A Tone, K Shikata, D Ogawa, S Sasaki… - Journal of the Renin …, 2007 - journals.sagepub.com
Introduction. Macrophages play critical roles in the development of atherosclerosis and
diabetic nephropathy as well as many inflammatory diseases. Angiotensin II type 1 receptor …

Immunosuppressive effect of angiotensin receptor blocker on stimulation of mice CTLs by angiotensin II

A Maeda, T Okazaki, M Inoue, T Kitazono… - International …, 2009 - Elsevier
While angiotensin II, which is produced by the renin–angiotensin–aldosterone system, is
considered to be the major regulator molecule that controls both the blood pressure and …