[HTML][HTML] Anti-PLA2R antibodies measured by ELISA predict long-term outcome in a prevalent population of patients with idiopathic membranous nephropathy

D Kanigicherla, J Gummadova, EA McKenzie… - Kidney international, 2013 - Elsevier
Antibodies to the phospholipase A2 receptor 1 (PLA2R1) have been reported in 70% of
cases of idiopathic membranous nephropathy (IMN). The genetic susceptibility of IMN has …

Intravenous cyclophosphamide as an alternative to the oral cyclophosphamide modified Ponticelli regimen for high-risk PLA2R-positive membranous nephropathy

G Ștefan, A Zugravu, S Stancu - Journal of Nephrology, 2023 - Springer
The mainstay of treatment for high-risk primary membranous nephropathy (MN) is the cyclic
steroid-oral cyclophosphamide (cs-oral CYC) regimen (modified Ponticelli regimen)[1] …

Efficacy and safety of different immunosuppressive therapies in patients with membranous nephropathy and high PLA2R antibody titer

L Deng, Q Huang, J Wang, K Luo, J Liu… - Frontiers in …, 2022 - frontiersin.org
Background: This study aimed to evaluate clinical features and prognosis and therapy
option of patients with different risk ranks based on antibody against the M-type …

PLA2R and membranous nephropathy: a 3 year prospective Australian study

PA Hill, JL McRae, KM Dwyer - Nephrology, 2016 - Wiley Online Library
Aim The phospholipase A2 receptor (PLA2R) is the major target antigen in idiopathic
membranous nephropathy (iMN). The aim of this prospective study was to determine the …

Prevalence of anti-phospholipase A2 receptor antibodies in Japanese patients with membranous nephropathy

S Akiyama, M Akiyama, E Imai, T Ozaki… - Clinical and …, 2015 - Springer
Background Membranous nephropathy (MN) is the leading cause of nephrotic syndrome in
adults. Anti-M-type phospholipase A2 receptor (anti-PLA2R) antibodies are found in most …

M-type phospholipase A2 receptor (PLA2R) glomerular staining in pediatric idiopathic membranous nephropathy

S Kanda, S Horita, T Yanagihara, A Shimizu… - Pediatric …, 2017 - Springer
Background Identifying M-type phospholipase A 2 receptor (PLA 2 R) is a landmark
breakthrough for understanding adult idiopathic membranous nephropathy (iMN). However …

Personalized medicine for PLA2R1-related membranous nephropathy: A multicenter randomized control trial

V Brglez, S Boyer-Suavet, K Zorzi, C Fernandez… - Frontiers in …, 2020 - frontiersin.org
Background: Membranous Nephropathy (MN) is a rare autoimmune disease related to
PLA2R1 antibodies in 70% of cases. One third of patients enter in spontaneous remission …

Serum anti-phospolipase A2 receptor antibodies and glomerular IgG4 in the diagnosis of membranous nephropathy

Y Guan, H LI, L Duan, Y LI, Y Wen… - Chinese Journal of …, 2015 - pesquisa.bvsalud.org
Objective To discuss the relationship between serum anti-Phosphalipase A2 receptor
(PLA2R) antibodies and glomerular IgG4 subclass in patients with membranous …

Evaluation of anti-PLA2R1 as measured by a novel ELISA in patients with idiopathic membranous nephropathy: a cohort study

SA Timmermans, JGMC Damoiseaux… - American journal of …, 2014 - academic.oup.com
Objectives: Autoantibodies against the M-type phospholipase A2 receptor 1 (anti-PLA2R1)
have been demonstrated to be very specific for idiopathic membranous nephropathy (MN) …

PLA2R-IgG4 antibody as a predictive biomarker of treatment effectiveness and prognostic evaluation in patients with idiopathic membranous nephropathy: a …

Y Huang, J Zhou, K Zhou, B Huang, J Xue, X Zhang… - PeerJ, 2022 - peerj.com
Background The Kidney Disease Improving Global Outcomes (KDIGO) 2021 guidelines
recommend Rituximab (RTX) as the first-line therapy and phospholipase A2 receptor …