Optimal value for serum anti-PLA2R antibody in primary membranous nephropathy: a multicenter observational study

J Chen, X Jia, X Wei, J Li, Y Liu, Y Lian, Z Cui… - American Journal of …, 2022 - karger.com
Introduction: Anti-phospholipase A2 receptor antibody (PLA2R-Ab) is highly specific for
primary membranous nephropathy (PMN). Here, we compare the diagnostic value of …

Membranous nephropathy: a journey from bench to bedside

JM Francis, LH Beck Jr, DJ Salant - American Journal of Kidney Diseases, 2016 - Elsevier
Lessons from an animal model that faithfully resembles human membranous nephropathy
(MN) have informed our understanding of the pathogenesis of this organ-specific …

Diagnostic accuracy of PLA2R autoantibodies and glomerular staining for the differentiation of idiopathic and secondary membranous nephropathy: an updated meta …

H Dai, H Zhang, Y He - Scientific reports, 2015 - nature.com
The diagnostic performance of M-type phospholipase A2 receptor (PLA2R) autoantibodies
and PLA2R glomerular staining in discriminating between idiopathic membranous …

[HTML][HTML] The relationship of anti-phospholipase A2 receptor antibody and C5a complement with disease activity and short-term outcome in idiopathic membranous …

JN Chi, TS Lai, CF Wu, TY Fu, YH Chou… - Journal of the Formosan …, 2019 - Elsevier
Background The binding of anti-phospholipase A2 receptor (anti-PLA2R) antibody to
podocyte and complement activation is the mechanisms of idiopathic membranous …

Analysis of glomerular IgG subclasses switch in idiopathic membranous nephropathy classified by glomerular phospholipase A2 receptor antigen and serum antibody

H Cui, C Li, H Li, Y Wen, L Duan, Y Li, X Yan… - Disease …, 2021 - Wiley Online Library
Background. The role of IgG subclass in idiopathic membranous nephropathy (IMN) was
unclarified. Recent study found IgG subtype switches from IgG1 to IgG4 in the early …

[HTML][HTML] PLA2R antibody does not outperform conventional clinical markers in predicting outcomes in membranous nephropathy

O Ragy, S Bate, S Bukhari, M Hiremath… - Kidney International …, 2023 - Elsevier
Introduction The prognostic value of PLA2R antibody (Ab) test in clinical practice remains
unclear. We aimed to evaluate its ability in predicting hard outcomes in primary …

Bortezomib treatment for refractory PLA2R-positive membranous nephropathy

AS Geara, V Bhoj, JJ Hogan - Glomerular diseases, 2021 - karger.com
Introduction: B-cell depletion has been shown to be an effective strategy for the majority of
patients with membranous nephropathy (MN), and in PLA2R-positive MN, immunologic …

Serum anti-PLA2R antibody and glomerular PLA2R deposition in Chinese patients with membranous nephropathy: a cross-sectional study

L Pang, AM Zhang, HX Li, JL Du, LL Jiao, N Duan… - Medicine, 2017 - journals.lww.com
M-type phospholipase A2 receptor (PLA2R) is the major target antigen in primary
membranous nephropathy (PMN). Previous studies have evaluated the diagnostic value of …

Combined Serologic and Genetic Risk Score and Prognostication of PLA2R-Associated Membranous Nephropathy

X Hu, J Xu, W Wang, L Liu, Y Jing, C Gao… - Clinical Journal of the …, 2024 - journals.lww.com
Methods: We performed a retrospective analysis of 519 biopsy-proven PLA2R-associated
primary membranous nephropathy patients with baseline eGFR≥ 25ml/min/1.73 m 2. The …

Accuracy of serum PLA2R antibody detected by indirect immunofluorescence in diagnosing biopsy-proven primary membranous nephropathy: A single-center …

M Allinovi, G Lugli, F Rossi, B Palterer… - Journal of …, 2023 - Springer
The M-type phospholipase A2 receptor autoreactive antibodies (PLA2R-Ab) represent the
leading cause of primary membranous nephropathy (pMN)[1]. Several studies report …