Endothelial cells represent one of the most abundant and widely found cell types in the
mammalian embryo. These cells arise in close proximity with and often as an integral part of …

Epidermal growth factor (EGF) is one of the major growth-promoting agents in milk. Using
immunohistochemistry we localized EGF in the mammary glands of lactating rats to the …

We have previously shown that isolated islets embedded in type 1 collagen gel in the
presence of a defined medium undergo transdifferentiation within 96 h to duct epithelial …

Epidermal growth factor (EGF) causes pituitary GH3 cells to change from their normal
predominantly rounded morphology to much more elongated cells with extensive filopodia …

Objectives: Recent studies have demonstrated the impressive expansion of β cells in vitro.
But unfortunately, expanded β cells do not function in the same way as fully differentiated β …

The distribution of epidermal growth factor (EGF) receptors was studied in the pancreas
using light microscopic autoradiography, which was performed at different time intervals (2 …

A detailed morphological map of pancreatic development has evolved over many years of
careful observation of embryonic growth, particularly in the mouse, providing a template for …

Diabetes, particularly type 1 diabetes, results from the lack of pancreatic β-cells. β-cell
replenishment can functionally reverse diabetes, but two critical challenges face the field: 1 …

Epidermal growth factor (EGF) is a potent inhibitor of adipose differentiation in vitro and
delays adipose tissue development in vivo. Here we show that in the homozygous male …

Epidermal growth factor (EGF) is synthesized in the pancreas and diabetic animals have low
levels of EGF. However, the role of EGF in regulating the major function of the pancreas …