Cerebral blood flow responses to changes in oxygen and carbon dioxide in humans
A Vovk, DA Cunningham, JM Kowalchuk… - Canadian journal of …, 2002 - cdnsciencepub.com
This study characterized cerebral blood flow (CBF) responses in the middle cerebral artery
to P CO2ranging from 30 to 60 mmHg (1 mmHg= 133.322 Pa) during hypoxia (50 mmHg) …
to P CO2ranging from 30 to 60 mmHg (1 mmHg= 133.322 Pa) during hypoxia (50 mmHg) …
Continuous neuromonitoring using transcranial Doppler reflects blood flow during carbon dioxide challenge in primates with global cerebral ischemia
OBJECTIVE: At present, there is no consensus on the optimal monitoring method for
cerebral blood flow (CBF) in neurointensive care patients. The aim of the present study was …
cerebral blood flow (CBF) in neurointensive care patients. The aim of the present study was …
Early nitric oxide increase in depolarized tissue of cat focal cerebral ischaemia
K Ohta, R Graf, G Rosner, E Kumura, WD Heiss - Neuroreport, 1996 - journals.lww.com
TISSUE nitric oxide (NO) concentration was investigated in relation to ion-homeostasis
disturbance in the cat model of focal cerebral ischaemia. An NO electrode, a Ca 2+ …
disturbance in the cat model of focal cerebral ischaemia. An NO electrode, a Ca 2+ …
Nitric oxide donors increase blood flow and reduce brain damage in focal ischemia: evidence that nitric oxide is beneficial in the early stages of cerebral ischemia
F Zhang, JG White, C Iadecola - Journal of Cerebral Blood …, 1994 - journals.sagepub.com
We studied whether administration of nitric oxide (NO) donors reduces the ischemic damage
resulting from middle cerebral artery (MCA) occlusion in spontaneously hypertensive rats …
resulting from middle cerebral artery (MCA) occlusion in spontaneously hypertensive rats …
Normobaric hyperoxia delays and attenuates early nitric oxide production in focal cerebral ischemic rats
Z Yuan, W Liu, B Liu, A Schnell, KJ Liu - Brain research, 2010 - Elsevier
Overproduction of neuronal nitric oxide synthase (nNOS)-derived NO is detrimental during
cerebral ischemia. Normobaric hyperoxia (NBO) has been shown to be neuroprotective …
cerebral ischemia. Normobaric hyperoxia (NBO) has been shown to be neuroprotective …
Nitric oxide contributes to functional hyperemia in cerebellar cortex
C Iadecola, J Li, TJ Ebner, X Xu - American Journal of …, 1995 - journals.physiology.org
We used the parallel fibers (PF) system of the cerebellar cortex as a model to investigate the
role of nitric oxide (NO) in the increases in blood flow elicited by neural activation. Rats were …
role of nitric oxide (NO) in the increases in blood flow elicited by neural activation. Rats were …
Impaired cerebrovascular reactivity after cortical spreading depression in rats: restoration by nitric oxide or cGMP
KEL Scheckenbach, JP Dreier, U Dirnagl… - Experimental …, 2006 - Elsevier
We investigated the role of the NO/cGMP system in the vasodilatory response to
hypercapnia after cortical spreading depression (CSD) in barbiturate anesthetized rats in …
hypercapnia after cortical spreading depression (CSD) in barbiturate anesthetized rats in …
Hemoglobin and cerebral hypoxic vasodilation in humans: Evidence for nitric oxide-dependent and S-nitrosothiol mediated signal transduction
RL Hoiland, DB MacLeod, BS Stacey… - Journal of Cerebral …, 2023 - journals.sagepub.com
Cerebral hypoxic vasodilation is poorly understood in humans, which undermines the
development of therapeutics to optimize cerebral oxygen delivery. Across four investigations …
development of therapeutics to optimize cerebral oxygen delivery. Across four investigations …
Cerebrovascular Vasodilation to Extraluminal Acidosis Occurs via Combined Activation of ATP-Sensitive and Ca2+-Activated Potassium Channels
U Lindauer, J Vogt, S Schuh-Hofer… - Journal of Cerebral …, 2003 - journals.sagepub.com
Albeit controversely discussed, it has been suggested by several authors that nitric oxide
(NO) serves as a permissive factor in the cerebral blood flow response to systemic …
(NO) serves as a permissive factor in the cerebral blood flow response to systemic …
The cerebrocortical microcirculatory effect of nitric oxide synthase blockade is dependent upon baseline red blood cell flow in the rat
Z Lacza, B Erdős, C Görlach, M Wahl, P Sándor… - Neuroscience …, 2000 - Elsevier
The effects of nitric oxide synthase (NOS) blockade on the cerebrocortical microcirculation
were investigated under physiological conditions in anesthetized ventilated rats using laser …
were investigated under physiological conditions in anesthetized ventilated rats using laser …