Conclusions: These must only be tentative as the balance order design is not complete, but
there is a suggestion that interaction effects may be occurring, particularly with metoprolol …

Previous investigations have suggested that hydrophilic β-Blockers, which appear at low
concentrations in brain tissue, are less likely to produce CNS-related side-effects than are …

Vivid and bizarre dreams, hallucinations, sleep disturbance and psychosis have all been
described following treatment with β-Blockers. It has been suggested that these central …

Beta-adrenergic blocking drugs are a widely used, well tolerated and effective treatment for
a variety of cardiovascular and noncardiovascular disorders. Over the years, beta-blockers …

Among the side effects commonly reported with the use of beta-blockers are symptoms
related to the central nervous system (CNS). In this study we compared the effects of four …

During the last four years we have used a new cardioselective β‐adrenergic blocking
substance, ICI 66.082 (atenolol or Tenormin®), alone or in combination with other drugs for …

One of the attributes of beta‐adrenergic blocking agents that has distinguished these drugs
from each other is degree of lipophilicity. While this feature may play a role in facilitating …

During the last decade β-adrenoceptor antagonists have become one of the first-line
treatments for hypertension. Generally, they have been shown to be safe with a low …

Beta-blockers are a class of drugs with important benefits in cardiovascular pathology. In this
paper, we aim to highlight their adverse and therapeutic effects in the neuropsychiatric field …

Central nervous system (CNS)‐related symptoms and quality of life during treatment with
controlled‐release (CR) metoprolol and a standard formulation of atenolol were compared …