The c-Jun NH2-terminal kinase (JNK) signal transduction pathway plays important roles in
cellular processes and stress. However, the role of JNK1 in intestinal homeostasis and …

Abstract c-Jun NH2-terminal kinase (JNK) links several cellular processes, including
proliferation and survival, and is believed to be involved in carcinogenesis. However, the …

The cJun NH2-terminal kinase (JNK) signal transduction pathway has been implicated in the
growth of carcinogen-induced hepatocellular carcinoma. However, the mechanism that …

Although the c-Jun NH2-terminal kinase (JNK) pathway has been implicated in mediating
cell growth and transformation, its downstream effectors remain to be identified. Using JNK2 …

The c-Jun NH2-terminal kinase (JNK) signaling cascade has been implicated in a wide
range of diseases, including cancer. It is unclear how different JNK proteins contribute to …

The three different c-Jun N-terminal kinases (JNKs) are activated in multiple cell typesby
both apoptotic and mitogenic signals, and in turn regulate the activity of transcriptionfactors …

Wnt signalling is a crucial signalling pathway controlling intestinal homeostasis and cancer.
We show here that the JNK MAP kinase pathway and one of its most important substrates …

JNK proteins have been shown to be involved in liver carcinogenesis in mice, but the extent
of their involvement in the development of human liver cancers is unknown. Here, we show …

c-Jun-N-terminal kinase (JNK) is a mitogen-activated protein kinase family member that is
activated by diverse stimuli, including cytokines (such as tumor necrosis factor and …

Abstract c-Jun NH2-terminal kinase (JNK) 1 and JNK2 have been assumed to complement
each other and mediate the same or similar biological functions. However, our recent reports …