Clinically, the term" drug interaction" is used when the prior or concurrent administration of
one drug causes an unusual or unexpected patient response to a second drug. The drug …

Drugs may frequently interact adversely to cause drug toxicity or render a needed therapy
ineffective. The situation is compounded by the current pattern of drug usage in which …

Drug interactions are usually classified as either pharmacokinetic or pharmacodynamic in
nature. Interactions in which one drug affects the absorption, distribution metabolism, or …

A drug interaction implies a likely modification of the expected response to the drug in an
individual, due to the exposure of the individual to one or more drugs or substances. Drug …

The mechanisms of drug interaction at major points within the pharmacodynamic phase of
drug activity are reviewed. A series of tables list common drug interactions and figures are …

During the last 20 years, the general problem of pharmacokinetic drug interactions has
received increasing attention. Over this period a number of new and unique classes of …

During the last 15–20 years the general problem of pharmacokinetic drug interactions has
received increasing attention. Over this period a number of new and unique classes of …

Open any current medical journal and one is reminded that the coadministration of two or
more drugs can either cause deleterious effects or lead to ineffective therapy. Those …

Pharmacokinetic drug–drug interactions can be explained as the interaction between two or
more different drug molecules after their coadministration or during their simultaneous …

Daniel A. Hussar is a professor of pharmacy and the director of the department of pharmacy
at the Philadelphia College of Pharmacy and Science. He teaches pharmacy and …