[HTML][HTML] Propionibacterium acnes strain populations in the human skin microbiome associated with acne

S Fitz-Gibbon, S Tomida, BH Chiu, L Nguyen… - Journal of investigative …, 2013 - Elsevier
The human skin microbiome has important roles in skin health and disease. However,
bacterial population structure and diversity at the strain level is poorly understood. We …

Pan-genome and comparative genome analyses of propionibacterium acnes reveal its genomic diversity in the healthy and diseased human skin microbiome

S Tomida, L Nguyen, BH Chiu, J Liu, E Sodergren… - mbio, 2013 - Am Soc Microbiol
Propionibacterium acnes constitutes a major part of the skin microbiome and contributes to
human health. However, it has also been implicated as a pathogenic factor in several …

Comparative Genomics and Transcriptomics of Propionibacterium acnes

E Brzuszkiewicz, J Weiner, A Wollherr, A Thürmer… - PLoS …, 2011 - journals.plos.org
The anaerobic Gram-positive bacterium Propionibacterium acnes is a human skin
commensal that is occasionally associated with inflammatory diseases. Recent work has …

[HTML][HTML] Different Propionibacterium acnes phylotypes induce distinct immune responses and express unique surface and secreted proteomes

Y Yu, J Champer, GW Agak, S Kao, RL Modlin… - Journal of Investigative …, 2016 - Elsevier
Propionibacterium acnes is a skin commensal bacterium that contributes to the development
of acne vulgaris and other infections. Recent work revealed that P. acnes clinical isolates …

Acne is not associated with yet-uncultured bacteria

M Bek-Thomsen, HB Lomholt… - Journal of clinical …, 2008 - Am Soc Microbiol
Current clinical and microbiological information on acne fails to demonstrate a clear
association between particular species, including Propionibacterium acnes, and disease …

Propionibacterium acnes and Acne Vulgaris: New Insights from the Integration of Population Genetic, Multi-Omic, Biochemical and Host-Microbe Studies

J McLaughlin, S Watterson, AM Layton, AJ Bjourson… - Microorganisms, 2019 - mdpi.com
The anaerobic bacterium Propionibacterium acnes is believed to play an important role in
the pathophysiology of the common skin disease acne vulgaris. Over the last 10 years our …

[HTML][HTML] What does it take to satisfy Koch's postulates two centuries later?: Microbial genomics and Propionibacteria acnes

JA Segre - Journal of Investigative Dermatology, 2013 - Elsevier
For two centuries, Koch's postulates have set the gold standard for establishing the
microbiological etiology of infection and disease. Genomic sequencing now brings finer …

Analysis of Complete Genomes of Propionibacterium acnes Reveals a Novel Plasmid and Increased Pseudogenes in an Acne Associated Strain

G Kasimatis, S Fitz-Gibbon, S Tomida… - BioMed research …, 2013 - Wiley Online Library
The human skin harbors a diverse community of bacteria, including the Gram‐positive,
anaerobic bacterium Propionibacterium acnes. P. acnes has historically been linked to the …

[HTML][HTML] Isolation and identification of the follicular microbiome: implications for acne research

JB Hall, Z Cong, Y Imamura-Kawasawa, BA Kidd… - Journal of Investigative …, 2018 - Elsevier
Our understanding of the microbiome and the role of Propionibacterium acnes in skin
homeostasis and acne pathogenesis is evolving. Multiple methods for sampling and …

The balance of metagenomic elements shapes the skin microbiome in acne and health

E Barnard, B Shi, D Kang, N Craft, H Li - Scientific reports, 2016 - nature.com
Studies have emphasized the importance of disease-associated microorganisms in
perturbed communities, however, the protective roles of commensals are largely under …