Clinical validation of 4-dimensional computed tomography ventilation with pulmonary function test data

D Brennan, L Schubert, Q Diot, R Castillo… - International Journal of …, 2015 - Elsevier
Purpose A new form of functional imaging has been proposed in the form of 4-dimensional
computed tomography (4DCT) ventilation. Because 4DCTs are acquired as part of routine …

Use of 4-dimensional computed tomography-based ventilation imaging to correlate lung dose and function with clinical outcomes

Y Vinogradskiy, R Castillo, E Castillo, SL Tucker… - International Journal of …, 2013 - Elsevier
PURPOSE: Four-dimensional computed tomography (4DCT)-based ventilation is an
emerging imaging modality that can be used in the thoracic treatment planning process. The …

Comparison of 4-dimensional computed tomography ventilation with nuclear medicine ventilation-perfusion imaging: a clinical validation study

Y Vinogradskiy, PJ Koo, R Castillo, E Castillo… - International Journal of …, 2014 - Elsevier
Purpose Four-dimensional computed tomography (4DCT) ventilation imaging provides lung
function information for lung cancer patients undergoing radiation therapy. Before 4DCT …

Pulmonary ventilation imaging based on 4-dimensional computed tomography: comparison with pulmonary function tests and SPECT ventilation images

T Yamamoto, S Kabus, C Lorenz, E Mittra… - International Journal of …, 2014 - Elsevier
Purpose 4-dimensional computed tomography (4D-CT)-based pulmonary ventilation
imaging is an emerging functional imaging modality. The purpose of this study was to …

A complete 4 DCT‐ventilation functional avoidance virtual trial: Developing strategies for prospective clinical trials

T Waxweiler, L Schubert, Q Diot… - Journal of applied …, 2017 - Wiley Online Library
Introduction 4 DCT‐ventilation is an exciting new imaging modality that uses 4 DCT data to
calculate lung‐function maps. Because 4 DCT s are acquired as standard of care for lung …

Reproducibility of four-dimensional computed tomography-based lung ventilation imaging

T Yamamoto, S Kabus, J Von Berg, C Lorenz… - Academic radiology, 2012 - Elsevier
RATIONALE AND OBJECTIVES: A novel ventilation imaging method based on four-
dimensional (4D) computed tomography (CT) has been applied to the field of radiation …

Assessing the use of 4 DCT‐ventilation in pre‐operative surgical lung cancer evaluation

Y Vinogradskiy, M Jackson, L Schubert… - Medical …, 2017 - Wiley Online Library
Purpose A primary treatment option for lung cancer patients is surgical resection. Patients
who have poor lung function prior to surgery are at increased risk of developing serious and …

Results of a multi-institutional phase 2 clinical trial for 4DCT-ventilation functional avoidance thoracic radiation therapy

Y Vinogradskiy, R Castillo, E Castillo, L Schubert… - International Journal of …, 2022 - Elsevier
Purpose Radiation pneumonitis remains a major limitation in the radiation therapy treatment
of patients with lung cancer. Functional avoidance radiation therapy uses functional imaging …

Interim analysis of a two-institution, prospective clinical trial of 4DCT-ventilation-based functional avoidance radiation therapy

Y Vinogradskiy, CG Rusthoven, L Schubert… - International Journal of …, 2018 - Elsevier
Purpose Functional imaging has been proposed that uses 4DCT images to calculate 4DCT-
based lung ventilation (4DCT-ventilation). We have started a 2-institution, phase 2 …

Evaluating the toxicity reduction with computed tomographic ventilation functional avoidance radiation therapy

AM Faught, Y Miyasaka, N Kadoya, R Castillo… - International Journal of …, 2017 - Elsevier
Purpose Computed tomographic (CT) ventilation imaging is a new modality that uses 4-
dimensional (4D) CT information to calculate lung ventilation. Although retrospective studies …