Th17/IL-17 Axis in HTLV-1-associated myelopathy tropical spastic Paraparesis and multiple sclerosis: novel insights into the immunity during HAMTSP
M Shafiei, SH Mozhgani - Molecular Neurobiology, 2023 - Springer
Human T lymphotropic virus–associated myelopathy/tropical spastic paraparesis
(HTLV/TSP), also known as HTLV-associated myelopathy/tropical spastic paraparesis …
(HTLV/TSP), also known as HTLV-associated myelopathy/tropical spastic paraparesis …
Molecular pathology of HTLV-1
U Bertazzoni, V Ciminale, MG Romanelli - Frontiers in Microbiology, 2018 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1) was the first human retrovirus discovered. It is
estimated that 10–20 million people are infected worldwide by this oncogenic virus. About 5 …
estimated that 10–20 million people are infected worldwide by this oncogenic virus. About 5 …
Functional changes in astrocytes by human T-lymphotropic virus type-1 T-lymphocytes
H Akaoka, R Szymocha, P Beurton-Marduel, A Bernard… - Virus Research, 2001 - Elsevier
The human T-lymphotropic virus type-1 (HTLV-1) is the causative agent of a chronic
progressive myelopathy (TSP/HAM) in which lesions of the central nervous system (CNS) …
progressive myelopathy (TSP/HAM) in which lesions of the central nervous system (CNS) …
Cellular tropism exhibited by human T lymphotropic virus type 1 (HTLV-1) and type 2 (HTLV-2)
Background HTLV-1 predominantly transforms CD4+ T cells in vitro and induces leukemia
and neurological disease in vivo, whereas HTLV-2 shows a preference for CD8+ T cell …
and neurological disease in vivo, whereas HTLV-2 shows a preference for CD8+ T cell …
Following the clues: usefulness of biomarkers of neuroinflammation and neurodegeneration in the investigation of HTLV-1-associated myelopathy progression
FS Souza, NL Freitas, YCP Gomes, RC Torres… - Frontiers in …, 2021 - frontiersin.org
Human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is a neurodegenerative disease due to axonal damage of the …
paraparesis (HAM/TSP) is a neurodegenerative disease due to axonal damage of the …
HTLV-1 infection and the viral etiology of multiple sclerosis
J Oger - Journal of the neurological sciences, 2007 - Elsevier
The HTLV-1 virus produces a progressive inflammatory, and then degenerative, myelopathy
which evolves progressively from onset. HTLV-1 in endemic in populations which are …
which evolves progressively from onset. HTLV-1 in endemic in populations which are …
In vitro cytoskeleton changes of mouse neurons induced by purified HTLV-1, and PBMC from HAM/TSP patients and HTLV-1 carriers
E Ramírez, L Cartier, R Flores - Archives of virology, 2004 - Springer
HTLV-1 is the causative agent of HAM/TSP. This neurological disease affects the CNS
producing damage of the motor tracts at the spinal cord. The HAM/TSP pathogenesis …
producing damage of the motor tracts at the spinal cord. The HAM/TSP pathogenesis …
The frequency of CD127low expressing CD4+CD25high T regulatory cells is inversely correlated with human T lymphotrophic virus type-1 (HTLV-1) proviral load in …
J Michaëlsson, HMR Barbosa, KA Jordan… - BMC immunology, 2008 - Springer
Background CD4+ CD25 high regulatory T (T Reg) cells modulate antigen-specific T cell
responses, and can suppress anti-viral immunity. In HTLV-1 infection, a selective decrease …
responses, and can suppress anti-viral immunity. In HTLV-1 infection, a selective decrease …
Therapeutic strategies in HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)
T Nakamura, Y Nishiura… - Central Nervous System …, 2009 - ingentaconnect.com
Human T lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is chronic progressive myelopathy characterized by bilateral …
paraparesis (HAM/TSP) is chronic progressive myelopathy characterized by bilateral …
Human stem cell models to study host–virus interactions in the central nervous system
O Harschnitz, L Studer - Nature Reviews Immunology, 2021 - nature.com
Advancements in human pluripotent stem cell technology offer a unique opportunity for the
neuroimmunology field to study host–virus interactions directly in disease-relevant cells of …
neuroimmunology field to study host–virus interactions directly in disease-relevant cells of …